School of Public Health, University of Alberta, Edmonton, Alberta, Canada
University of Alberta, Edmonton, Alberta, Canada.
BMJ Open. 2023 Aug 22;13(8):e071321. doi: 10.1136/bmjopen-2022-071321.
To construct a machine-learning (ML) model for health systems with organised falls prevention programmes to identify older adults at risk for fall-related admissions.
This prognostic study used population-level administrative health data to develop an ML prediction model.
This study took place in Alberta, Canada during 2018-2019.
Albertans aged 65 and older with at least one prior admission. Those with palliative conditions or emigrated out of Alberta were excluded.
Unit of analysis was the individual person.
MAIN OUTCOMES/MEASURES: We identified fall-related admissions. A CatBoost model was developed on 2018 data to predict risk of fall-related emergency department visits or hospitalisations. Temporal validation was done using 2019 data to evaluate model performance. We reported discrimination, calibration and other relevant metrics measured at the end of 2019 on both ranked predictions and predicted probability thresholds. A cost-savings simulation was performed using 2019 data.
Final number of study participants was 224 445. The validation set had 203 584 participants with 19 389 fall-related events (9.5% pretest probability) and an ML model c-statistic of 0.70. The highest ranked predictions had post-test probabilities ranging from 40% to 50%. Net benefit analysis presented mixed results with some net benefit using the ML model in the 6%-30% range. The top 50 percentile of predicted risks represented nearly $C60 million in health system costs related to falls. Intervening on the top 25 or 50 percentiles of predicted risk could realise substantial (up to $C16 million) savings.
ML prediction models based on population-level administrative data can assist health systems with fall prevention programmes identify older adults at risk of fall-related admissions and reduce costs. ML predictions based on ranked predictions or probability thresholds could guide subsequent interventions to mitigate fall risks. Increased access to diverse forms of data could improve ML performance and further reduce costs.
构建一个具有组织性跌倒预防计划的医疗保健系统的机器学习(ML)模型,以识别有跌倒相关入院风险的老年人。
本预后研究使用人群水平的行政健康数据来开发 ML 预测模型。
本研究于 2018 年至 2019 年在加拿大艾伯塔省进行。
年龄在 65 岁及以上且至少有一次既往入院记录的艾伯塔省人。排除有姑息治疗条件或已移民出艾伯塔省的人。
分析单位是个人。
主要结果/措施:我们确定了与跌倒相关的入院记录。在 2018 年的数据上开发了一个 CatBoost 模型来预测与跌倒相关的急诊就诊或住院的风险。使用 2019 年的数据进行时间验证,以评估模型性能。我们在 2019 年末报告了排名预测和预测概率阈值的区分度、校准和其他相关指标。使用 2019 年的数据进行了成本节约模拟。
最终研究参与者总数为 224445 人。验证集中有 203584 名参与者,发生了 19389 例与跌倒相关的事件(9.5%的先验概率),ML 模型的 C 统计量为 0.70。排名最高的预测结果的后验概率范围从 40%到 50%。净效益分析结果不一,在 6%-30%的范围内,使用 ML 模型有净效益。预测风险的前 50%代表了与跌倒相关的近 6000 万加元的卫生系统成本。干预预测风险的前 25%或 50%可能会产生大量(高达 1600 万加元)的节省。
基于人群水平行政数据的 ML 预测模型可以帮助具有跌倒预防计划的医疗保健系统识别有跌倒相关入院风险的老年人,并降低成本。基于排名预测或概率阈值的 ML 预测可以指导后续干预措施以降低跌倒风险。增加对各种形式数据的访问可以提高 ML 性能并进一步降低成本。