School of Medicine, West Virginia University, Morgantown, WV, USA.
Department of Otolaryngology, West Virginia University, Morgantown, WV, USA.
Ann Otol Rhinol Laryngol. 2024 Feb;133(2):169-173. doi: 10.1177/00034894231195662. Epub 2023 Aug 22.
To identify the differences in the impact of chronic rhinosinusitis (CRS) between female and male adolescent patients at presentation.
Cross sectional study.
Adolescent patients, age 12 to 18 years old, presenting to our Otolaryngology clinic between August 2020 and April 2023 for CRS were asked to fill both the SNOT-22 and the SN5 forms. Female and male cohorts were compared regarding their demographics, comorbidities, subjective and objective disease measurements, and choice of treatment.
Sixty-six patients were included, 30 female and 36 male patients. There were no differences in age, allergic rhinitis, asthma, obstructive sleep apnea, presence of nasal septal deviation, and objective disease severity ( > .05 for all). At presentation, mean overall SNOT-22, ear/facial, sleep, and psychological domains were all higher in female patients (43vs 30.9, = .02; 9.1vs 6, = .03; 11.8vs 8.3, = .07; 14.1vs 8.8, = .02 respectively). SN5 scores and overall QoL visual analog scale were similar in females and males.
Female patients with CRS show higher subjective disease burden. Incorporating data on gender-specific differences may be important to personalize treatment decision making.
确定女性和男性青少年患者初诊时慢性鼻-鼻窦炎（CRS）的影响差异。
横断面研究。
2020 年 8 月至 2023 年 4 月期间，我们耳鼻喉科诊所就诊的年龄在 12 至 18 岁之间的青少年 CRS 患者被要求填写 SNOT-22 和 SN5 问卷。比较女性和男性队列在人口统计学、合并症、主观和客观疾病测量以及治疗选择方面的差异。
共纳入 66 例患者，其中 30 例为女性，36 例为男性。两组在年龄、变应性鼻炎、哮喘、阻塞性睡眠呼吸暂停、鼻中隔偏曲存在和客观疾病严重程度方面无差异（均> .05）。初诊时，女性患者的总体 SNOT-22、耳部/面部、睡眠和心理领域评分均高于男性（43 比 30.9，= .02；9.1 比 6，= .03；11.8 比 8.3，= .07；14.1 比 8.8，= .02）。女性和男性的 SN5 评分和总体生活质量视觉模拟评分相似。
女性 CRS 患者的主观疾病负担更高。纳入性别差异数据可能对制定个性化治疗决策很重要。
