Department of Otolaryngology, West Virginia University, Morgantown, West Virginia, USA.
School of Medicine, West Virginia University, Morgantown, West Virginia, USA.
Laryngoscope. 2023 May;133(5):1052-1058. doi: 10.1002/lary.30232. Epub 2022 May 31.
To validate each of the sino-nasal outcome test (SNOT-22) and the sinus and nasal quality of life (SN5) surveys for the adolescent population defined as 12 to 18 years old, and to determine if they correlate in regard to reports of sinonasal symptoms and quality of life.
Cross-sectional study.
Adolescent patients, age 12 to 18 years old, presenting to our otolaryngology clinic between August 2020 and June 2021 were asked to fill both the SNOT-22 and the SN5 forms. Demographics and comorbidities were reviewed. Patients recruited were then divided into a sinonasal cohort (those with chronic sinonasal symptoms) and a control cohort (those who did not have any sinonasal disorders at time of visit).
One hundred fifteen patients completed both surveys, 80 patients in the sinonasal cohort and 35 patients in the control cohort. Average age was 14.9 years, and 49.6% were female. Mean SNOT-22 and SN5 scores were significantly higher in the sinonasal cohort as compared with the control cohort which confirmed validity of both surveys for the adolescents. Good test-retest reliability for both surveys was obtained (r = 0.76 for SNOT-22, and r = 0.64 for SN5). SNOT-22 and SN5 scores correlated well in both the sinonasal cohort (r = 0.63, p < 0.0001) and the control cohort (r = 0.61, p = 0.0003). Both surveys strongly predicted chronic sinonasal disorders with an odds ratio of 2.5 for SNOT-22 and 2.2 for SN5.
Both instruments can be used to study the outcome of treatment for sinonasal disorders in adolescent patients.
4 Laryngoscope, 133:1052-1058, 2023.
验证专为 12 至 18 岁青少年人群定义的鼻-鼻窦结局测试（SNOT-22）和鼻窦与鼻腔生活质量（SN5）调查问卷各自的有效性，并确定它们在报告鼻-鼻窦症状和生活质量方面是否存在相关性。
横断面研究。
2020 年 8 月至 2021 年 6 月间，我们招募了在耳鼻喉科门诊就诊的年龄在 12 至 18 岁的青少年患者，要求他们填写 SNOT-22 和 SN5 调查问卷。我们回顾了患者的人口统计学和合并症数据。随后，将招募的患者分为鼻-鼻窦组（存在慢性鼻-鼻窦症状的患者）和对照组（就诊时无任何鼻-鼻窦疾病的患者）。
共有 115 名患者完成了这两项调查，其中 80 名患者在鼻-鼻窦组，35 名患者在对照组。患者平均年龄为 14.9 岁，49.6%为女性。与对照组相比，鼻-鼻窦组的 SNOT-22 和 SN5 评分平均值显著更高，证实了这两项调查对青少年的有效性。两项调查都获得了良好的测试-重测信度（SNOT-22 的 r 值为 0.76，SN5 的 r 值为 0.64）。在鼻-鼻窦组（r=0.63，p<0.0001）和对照组（r=0.61，p=0.0003）中，SNOT-22 和 SN5 评分都有很好的相关性。这两项调查都强烈预测了慢性鼻-鼻窦疾病，SNOT-22 的优势比为 2.5，SN5 的优势比为 2.2。
这两种工具都可用于研究青少年患者鼻-鼻窦疾病治疗结果。
4 Laryngoscope, 133:1052-1058, 2023.
