School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Medical Practitioners Occupational Safety and Health, Vancouver Coastal Health, Vancouver, BC, Canada.
Front Public Health. 2023 Aug 7;11:1214093. doi: 10.3389/fpubh.2023.1214093. eCollection 2023.
The COVID-19 pandemic highlighted hurdles for healthcare delivery and personnel globally. Vaccination has been an important tool for preventing severe illness and death in healthcare workers (HCWs) as well as the public at large. However, vaccination has resulted in some HCWs requiring time off work post-vaccination to recover from adverse events. We aimed to understand which HCWs needed to take time off work post-vaccination, for which vaccine types and sequence, and how post-vaccination absence impacted uptake of booster doses in a cohort of 26,267 Canadian HCWs. By March 31, 2022, more than 98% had received at least two doses of the approved COVID-19 vaccines, following a two-dose mandate. We found that recent vaccination and longer intervals between doses were associated with significantly higher odds of time-loss, whereas being a medical resident and receiving the BNT162b2 vaccine were associated with lower odds. A history of lab-confirmed SARS-CoV-2 infection was associated with lower odds of receiving a booster dose compared with no documented infection, aOR 0.61 (95% CI: 0.55, 0.68). Similarly, taking sick time following the first or second dose was associated with lower odds of receiving a booster dose, aOR 0.83 (95% CI: 0.75, 0.90). As SARS-CoV-2 becomes endemic, the number and timing of additional doses for HCWs requires consideration of prevention of illness as well as service disruption from post-vaccination time-loss. Care should be taken to ensure adequate staffing if many HCWs are being vaccinated, especially for coverage for those who are more likely to need time off to recover.
新冠疫情凸显了全球医疗保健服务和人员面临的障碍。疫苗接种是预防医护人员（HCWs）和公众重症和死亡的重要工具。然而，疫苗接种导致一些 HCWs 在接种后需要休假以从不良反应中恢复。我们旨在了解在接种疫苗后哪些 HCWs 需要休假、接种哪种疫苗类型和接种顺序，以及接种后缺勤对 26267 名加拿大 HCWs 加强剂量接种率的影响。截至 2022 年 3 月 31 日，在两剂疫苗接种任务之后，超过 98%的人至少接种了两剂批准的 COVID-19 疫苗。我们发现，最近接种疫苗和两次接种之间的间隔时间较长与缺勤的几率显著增加相关，而作为医学住院医师并接种 BNT162b2 疫苗与较低的几率相关。与无记录感染相比，实验室确诊的 SARS-CoV-2 感染史与接受加强剂量的几率较低相关，比值比（aOR）为 0.61（95%可信区间：0.55，0.68）。同样，在接种第一或第二剂后请病假与接受加强剂量的几率较低相关，aOR 为 0.83（95%可信区间：0.75，0.90）。随着 SARS-CoV-2 成为地方病，HCWs 需要考虑接种更多剂次的数量和时间，既要预防疾病，也要考虑接种后缺勤对服务的影响。如果许多 HCWs 正在接种疫苗，应注意确保有足够的人员配备，特别是对于那些更有可能需要休假以恢复的人员。
