Yang Hongbo, Xu Wangguo, Tang Rubo, Zhang Meng, Song Yanan, Cao Jiatian, Zhang Feng, Huang Zheyong, Qian Juying, Ge Junbo
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai, China.
Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
JACC Asia. 2023 Jun 27;3(4):678-682. doi: 10.1016/j.jacasi.2023.04.001. eCollection 2023 Aug.
Side branch (SB) occlusion remains challenging in bifurcation percutaneous coronary intervention. We have introduced a novel method to protect SB named double kissing inflation outside the stent (DKo), which features twice inflation of protective balloon kissing with stent and postdilation balloon. This study compared protective effects of DKo vs jailed balloon technique (JBT) for bifurcation. This retrospective, single-center study enrolled 875 consecutive bifurcation lesions receiving either DKo (n = 209) or JBT (n = 666). At the 12-month follow-up, major adverse cardiac event occurred less in DKo (6.7% vs 12.0%; = 0.042), even in 1:2 propensity score matching analysis (6.4% vs 12.3%; = 0.034). Rewiring and transient SB loss occurred also less in DKo (0.5% vs 13.8% [ < 0.001]; 0.5% vs 4.8% [ = 0.003]). Similar results were observed in matching analysis. This study demonstrated DKo protected SB better than JBT in bifurcation percutaneous coronary intervention.
在分叉病变经皮冠状动脉介入治疗中,边支(SB)闭塞仍然是一个具有挑战性的问题。我们引入了一种名为支架外双重吻合法球囊扩张(DKo)的保护边支的新方法,其特点是保护球囊与支架及后扩张球囊进行两次吻合法球囊扩张。本研究比较了DKo与球囊拘禁技术(JBT)对分叉病变的保护效果。这项回顾性单中心研究纳入了875例连续的分叉病变患者,这些患者接受了DKo(n = 209)或JBT(n = 666)治疗。在12个月的随访中,DKo组发生主要不良心脏事件的比例较低(6.7%对12.0%;P = 0.042),即使在1:2倾向评分匹配分析中也是如此(6.4%对12.3%;P = 0.034)。DKo组的重新导丝操作和短暂边支丢失也较少(0.5%对13.8% [P < 0.001];0.5%对4.8% [P = 0.003])。在匹配分析中也观察到了类似的结果。本研究表明,在分叉病变经皮冠状动脉介入治疗中,DKo对边支的保护作用优于JBT。