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改良的冠状动脉分叉病变预扩张支架置入方法:“囚禁球囊技术”的临床应用。

A modified provisional stenting approach to coronary bifurcation lesions: clinical application of the "jailed-balloon technique".

机构信息

Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

J Interv Cardiol. 2012 Jun;25(3):289-96. doi: 10.1111/j.1540-8183.2011.00716.x. Epub 2012 Feb 26.

Abstract

OBJECTIVES

To demonstrate the application of a novel provisional side branch (SB) stenting strategy for coronary bifurcation lesions using a "jailed-balloon" technique (JBT).

BACKGROUND

Adverse cardiac events are higher for percutaneous coronary intervention (PCI) of bifurcation lesions. Recent studies support the use of provisional SB stenting, but a risk of SB closure and a higher rate of target lesion revascularization (TLR) remain important limitations.

METHODS

From December 2007 to August 2010, 100 patients with 102 bifurcation lesions underwent PCI using the JBT. Baseline and postprocedural quantitative coronary angiography (QCA) analysis were performed. Procedural and immediate clinical outcomes were reviewed.

RESULTS

The majority of patients presented with acute coronary syndrome (68%) and had Medina class 1,1,1 bifurcation lesions (91%). TIMI 3 flow was established in 100% of main branch and 99% of SB lesions. QCA revealed preservation of the bifurcation angle after PCI (pre-PCI: 59.6 ± 30.0; post-PCI: 63.3 ± 26.8, P = 0.41). Nine patients (9%) had lesions that required rewiring and two patients (2%) required provisional stenting of the SB. SB loss occurred in one patient (1%). The jailed-balloon or wire was not entrapped during any PCI. One patient (1%) suffered a periprocedural myocardial infarction (MI).

CONCLUSIONS

Provisional stenting of complex coronary bifurcation lesions using a JBT is associated with a high procedural success rate, improved SB patency, and a low rate of immediate cardiac events. Further study is warranted to evaluate the role of JBT in improving long-term clinical outcomes in PCI of complex bifurcation lesions.

摘要

目的

展示一种使用“球囊拘禁”技术(JBT)的新型冠状动脉分叉病变分支血管(SB)临时支架置入策略的应用。

背景

经皮冠状动脉介入治疗(PCI)分叉病变的心脏不良事件发生率较高。最近的研究支持使用临时 SB 支架置入术,但 SB 闭塞风险和更高的靶病变血运重建(TLR)率仍然是重要的局限性。

方法

2007 年 12 月至 2010 年 8 月,100 例 102 处分叉病变患者接受了 JBT 的 PCI。进行了基线和术后定量冠状动脉造影(QCA)分析。回顾了手术过程和即时临床结果。

结果

大多数患者表现为急性冠状动脉综合征(68%),并具有 Medina 1,1,1 型分叉病变(91%)。100%的主支和 99%的 SB 病变均建立了 TIMI 3 级血流。PCI 后保留了分叉角度(PCI 前:59.6±30.0;PCI 后:63.3±26.8,P=0.41)。9 例(9%)患者的病变需要重新布线,2 例(2%)患者需要临时 SB 支架置入。1 例(1%)患者 SB 丢失。在任何 PCI 过程中,都没有球囊或导丝被拘禁。1 例(1%)患者发生围手术期心肌梗死(MI)。

结论

使用 JBT 对复杂冠状动脉分叉病变进行临时支架置入术与高的手术成功率、改善 SB 通畅率和低的即刻心脏不良事件发生率相关。需要进一步研究来评估 JBT 在改善复杂分叉病变 PCI 长期临床结局中的作用。

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