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基于 DNA 探针和 PCR 的分子阴道炎检测的诊断性能。

Diagnostic performance of DNA probe-based and PCR-based molecular vaginitis testing.

机构信息

Department of Pathology and Laboratory Medicine Services, Central Texas Veterans Health Care System , Temple, Texas, USA.

Department of Research, Central Texas Veterans Health Care System , Temple, Texas, USA.

出版信息

Microbiol Spectr. 2023 Oct 17;11(5):e0162823. doi: 10.1128/spectrum.01628-23. Epub 2023 Aug 24.

Abstract

Using retrospective data from U.S. Food and Drug Administration-approved/cleared molecular vaginal panels, molecular methods were found to have higher detection for vaginitis and lower detection for bacterial vaginitis when compared to probe-based methods. In addition, the differentiation of and non- yeast has not reached the physician community as we observed noncompliance in recommended therapy. Furthermore, the pros and cons of migrating to molecular testing from conventional microscopy for identifying bacterial vaginitis and fungal vaginitis have been examined and reported in this paper. Interestingly, the mean (SD) age for patients with was 40.5 (40.0-41.1) years. Patients with were 5.2-8.1 (mean 6.7) years older than patients with .

摘要

利用美国食品和药物管理局批准/认证的分子阴道面板的回顾性数据,与基于探针的方法相比,分子方法在检测阴道炎方面的检出率更高,而在检测细菌性阴道炎方面的检出率更低。此外,当我们观察到不符合推荐治疗方案时, 与非酵母的区分尚未在医生群体中得到认可。此外,本文还探讨并报告了从传统显微镜检查转向分子检测以识别细菌性阴道炎和霉菌性阴道炎的优缺点。有趣的是, 患者的平均(SD)年龄为 40.5(40.0-41.1)岁。 患者比 患者年长 5.2-8.1(平均 6.7)岁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb9b/10581173/0d6a26e77925/spectrum.01628-23.f001.jpg

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