Servicio de Microbiología, Hospital Universitario de Álava, Instituto de Investigación Biosanitaria, BioAraba, Osakidetza-Servicio Vasco de Salud. c/ Francisco Leandro de Viana, s/n., 01009, Vitoria-Gasteiz, Álava, Spain.
Eur J Clin Microbiol Infect Dis. 2019 May;38(5):877-882. doi: 10.1007/s10096-019-03480-8. Epub 2019 Jan 26.
The aim of this study was to evaluate the BD MAX™ vaginal panel in the diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis by comparing it with conventional methods: (i) combination of Hay criteria and presence of clue cells with predominant growth of Gardnerella vaginalis, (ii) yeast culture, and (iii) combination of culture, wet mount microscopic examination, and an alternative molecular assay. One thousand vaginal samples of women ≥ 14 years were analyzed; 5% of the samples belonged to pregnant women. 19.3% were classified as BV, in 33.6% yeasts were recovered and in 1.5% TV was detected. For BV, sensitivity and specificity were of 89.8% and 96.5%, respectively; for VVC, sensitivity and specificity were of 97.4% and 96.8%, respectively, and for T. vaginalis, the sensitivity and specificity were of 100%. The BD MAX™ vaginal panel is highly sensitive and specific and simplifies the identification of infectious vaginitis.
本研究旨在通过与传统方法比较，评估 BD MAX™阴道面板在细菌性阴道病（BV）、外阴阴道念珠菌病（VVC）和滴虫病诊断中的应用：（i）将海氏标准与线索细胞存在以及阴道加德纳菌优势生长相结合，（ii）酵母培养，以及（iii）培养、湿片显微镜检查和替代分子检测相结合。分析了 1000 例年龄≥14 岁女性的阴道样本；5%的样本属于孕妇。19.3%的样本被归类为 BV，33.6%的样本中回收了酵母菌，1.5%的样本中检测到 TV。对于 BV，敏感性和特异性分别为 89.8%和 96.5%；对于 VVC，敏感性和特异性分别为 97.4%和 96.8%，对于 TV，敏感性和特异性分别为 100%。BD MAX™阴道面板具有高度的敏感性和特异性，简化了传染性阴道炎的鉴定。
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