Gratsianskiĭ N A, Panchenko E P, Agapov A A, Logutov Iu A, Vladimirov S S
Kardiologiia. 1986 Jun;26(6):38-43.
Intracoronary thrombolytic infusions were used in 10 patients with unstable angina and high risk of myocardial infarction (MI). Streptokinase (500,000 units per hour) was used in 9 patients, and urokinase, in one. Vascular recanalization was achieved in 4 cases where angiography showed coronary arterial occlusion by a thrombus. Myocardial infarction developed in 8 patients (large-focal in 6 and small-focal in 2) within 1 to 16 days after the thrombolytic infusion. Therefore, short-term local thrombolytic infusion fails to prevent myocardial infarction in patients with unstable angina.
10例有不稳定型心绞痛且心肌梗死（MI）高危的患者接受了冠状动脉内溶栓输注。9例患者使用链激酶（每小时500,000单位），1例使用尿激酶。4例血管造影显示冠状动脉被血栓阻塞的患者实现了血管再通。8例患者在溶栓输注后1至16天内发生心肌梗死（6例为大片灶性，2例为小片灶性）。因此，短期局部溶栓输注未能预防不稳定型心绞痛患者发生心肌梗死。
