Gasilin V S, Sidorenko B A, Lupanov V P, Sidel'nikova T Ia, Dorofeeva Z Z
Kardiologiia. 1986 Jul;26(7):12-9.
A prospective five-year study and medicinal treatment were conducted in 317 coronary patients with stable angina in the absence of any signs of heart failure, and stenosing coronary arterial atherosclerosis as evidenced by selective coronary angiography. Total mortality was 2.8%, and the incidence of documented non-fatal myocardial infarction was 3.8% per year. The mortality was mostly dependent on the severity of angina's functional class and the number of affected major coronary arteries (narrowed by more than 70%). A group of patients with unfavorable prognosis was identified (functional class III to IV, low physical stress tolerance, the involvement of two or three major coronary arteries). The results demonstrate the efficiency of long-term medication in coronary patients with stable angina due to stenosing coronary atherosclerosis.
对317例无心力衰竭迹象且经选择性冠状动脉造影证实有冠状动脉狭窄性动脉粥样硬化的稳定型心绞痛冠心病患者进行了一项为期五年的前瞻性研究及药物治疗。总死亡率为2.8%,每年有记录的非致命性心肌梗死发生率为3.8%。死亡率主要取决于心绞痛功能分级的严重程度以及受累主要冠状动脉的数量(狭窄超过70%)。确定了一组预后不良的患者(功能分级为III至IV级、身体应激耐受性低、两支或三支主要冠状动脉受累)。结果表明,对于因冠状动脉狭窄性动脉粥样硬化导致的稳定型心绞痛冠心病患者,长期药物治疗是有效的。