Omori Hisaki, Hata Masahiro, Kobayashi Matasaburo, Miyazaki Yuki, Hirashima Atsuya, Takahashi Shun, Ikeda Manabu
Department of Psychiatry Osaka University Graduate School of Medicine Osaka Japan.
Department of Psychiatry Esaka Hospital Osaka Japan.
PCN Rep. 2024 Jul 16;3(3):e227. doi: 10.1002/pcn5.227. eCollection 2024 Sep.
Electroconvulsive therapy (ECT) is widely recognized as one of the most effective treatments for various psychiatric disorders and is generally considered safe. However, a few reports have mentioned that multiple ECT sessions could induce electroencephalography (EEG) abnormalities and epileptic seizures, a serious side effect of ECT. We experienced a case with EEG abnormalities after multiple ECT sessions and aimed to share our insights on conducting ECT safely.
We present the case of a 73-year-old female diagnosed with major depressive disorder. She underwent regular ECT sessions to alleviate her psychiatric symptoms. However, after more than 80 sessions, previously undetected EEG abnormalities were observed. Since the patient did not have clinical seizures, we were able to continue ECT at longer intervals without the use of antiepileptic drugs.
Our case suggests the importance of routine EEG testing in patients undergoing prolonged ECT. While careful monitoring is necessary, continuing ECT without antiepileptic medication in patients with EEG abnormalities could be permissible.
电休克疗法（ECT）被广泛认为是治疗各种精神障碍最有效的方法之一，通常被认为是安全的。然而，有一些报告提到多次ECT治疗可能会诱发脑电图（EEG）异常和癫痫发作，这是ECT的一种严重副作用。我们遇到了一例在多次ECT治疗后出现EEG异常的病例，并旨在分享我们对安全进行ECT的见解。
我们介绍了一名73岁被诊断为重度抑郁症的女性病例。她接受了常规的ECT治疗以缓解其精神症状。然而，在超过80次治疗后，观察到了之前未被发现的EEG异常。由于该患者没有临床癫痫发作，我们能够在不使用抗癫痫药物的情况下以更长的间隔继续进行ECT治疗。
我们的病例表明，对于接受长时间ECT治疗的患者，常规EEG检查很重要。虽然仔细监测是必要的，但对于有EEG异常的患者，在不使用抗癫痫药物的情况下继续进行ECT治疗可能是可行的。
