Liu Jianzhi, Zheng Qiaoling, Shi Liangwen, Zhao Zhiwei, Chen Xuxiang, Wang Taiqin, Chen Xiaoqiang
Department of Otolaryngology Fujian Medical University Union Hospital Fuzhou Fujian China.
Department of Pathology Fujian Medical University Union Hospital Fuzhou Fujian China.
Laryngoscope Investig Otolaryngol. 2023 Jun 2;8(4):865-869. doi: 10.1002/lio2.1086. eCollection 2023 Aug.
To explore the clinical and laboratory features, therapy and prognosis of Kikuchi-Fujimoto disease (KFD) in the cervical region.
We retrospectively reviewed the medical records of 134 patients who were diagnosed and treated with KFD from January 2000 to May 2022 in Fujian Medical University Union Hospital (Fujian, China). Their clinical characteristics, affected lymph node size, imaging examinations, and laboratory study results were analyzed.
The mean patient age was 24.9 years, and the male-female ratio was 1:1.73. Fever (55.2%, = 74) was the most common clinical manifestation. Leukopenia (49.3%) was the commonest reported laboratory abnormality. A majority (65.7%) of the 134 patients presented with bilateral nodal involvement.
KFD should be considered as a possible diagnosis in a female patient under the age of 30 presenting with cervical lymphadenopathy, fever, leukopenia, and elevated LDH.
探讨颈部菊池-藤本病（KFD）的临床和实验室特征、治疗及预后。
我们回顾性分析了2000年1月至2022年5月在福建医科大学附属协和医院（中国福建）诊断并接受治疗的134例KFD患者的病历。分析了他们的临床特征、受累淋巴结大小、影像学检查及实验室研究结果。
患者平均年龄为24.9岁，男女比例为1:1.73。发热（55.2%，n = 74）是最常见的临床表现。白细胞减少（49.3%）是最常见的实验室异常报告。134例患者中大多数（65.7%）表现为双侧淋巴结受累。
对于出现颈部淋巴结病、发热、白细胞减少和乳酸脱氢酶升高的30岁以下女性患者，应考虑KFD作为可能的诊断。
4级。
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