Mahmood Ali, Mir Rabia, Salama Salama R, Miarrostami Rameen M, Lapidus Claudia, Pujol Fernando
New York Methodist Hospital, New York, NY, USA.
Yale J Biol Med. 2006 Mar;79(1):27-33.
Kikuchi's disease, or necrotizing histiocytic lymphadenitis, is a rare disease that presents predominantly in young women in their 20s and 30s from the Far East. Our case depicts an African-American male, in his sixth decade of life, presenting with Kikuchi's disease, making our case unusual. The clinical presentation, together with laboratory and pathological tests described here, specifically the utilization of immunohistochemistry, aid in establishing a diagnosis. We advocate the use of steroids as symptomatic therapy and provide a novel and successful therapeutic regimen. We do not recommend antibiotic therapy until an infectious etiology is confirmed.
菊池病，即坏死性组织细胞性淋巴结炎，是一种罕见疾病，主要见于远东地区二三十岁的年轻女性。我们的病例描述的是一名60岁的非裔美国男性患有菊池病，这使我们的病例不同寻常。这里描述的临床表现以及实验室和病理检查，特别是免疫组织化学的应用，有助于确诊。我们主张使用类固醇进行对症治疗，并提供了一种新颖且成功的治疗方案。在确认感染病因之前，我们不建议使用抗生素治疗。
