Baenas Diego F, Diehl Fernando A, Haye Salinas María J, Riva Verónica, Diller Ana, Lemos Pablo A
Clinical Medicine Department.
Rheumatology Department.
Int Med Case Rep J. 2016 Jun 29;9:163-7. doi: 10.2147/IMCRJ.S106396. eCollection 2016.
Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is an infrequent idiopathic disorder. It has been associated with autoimmune disorders, of which systemic lupus erythematosus is the most outstanding. The basis of its diagnosis relies on the histological examination of lymph nodes, which typically reveals necrosis surrounded by histiocytes with crescentic nucleus, immunoblasts and plasma cells, and absence of neutrophils. We report the case of a 27-year-old Argentinian female patient without any relevant past medical history to demonstrate the correlation between Kikuchi-Fujimoto disease and systemic lupus erythematosus.
菊池-藤本病，即组织细胞坏死性淋巴结炎，是一种罕见的特发性疾病。它与自身免疫性疾病有关，其中系统性红斑狼疮最为突出。其诊断依据依赖于淋巴结的组织学检查，典型表现为坏死灶周围有核呈新月形的组织细胞、免疫母细胞和浆细胞，且无中性粒细胞。我们报告一例27岁无相关既往病史的阿根廷女性患者，以证明菊池-藤本病与系统性红斑狼疮之间的相关性。
