Jedeikin R, Kaplan R, Shapira A, Radwan H, Hoffman S
Crit Care Med. 1979 Apr;7(4):168-70. doi: 10.1097/00003246-197904000-00004.
The insecticide Endrin is a highly toxic chlorinated hydrocarbon which can cause severe CNS and respiratory derangement. Death usually follows intoxication within 24 hours. A 19-year-old male developed convulsions and gross pulmonary edema after the ingestion of Endrin. His trachea was intubated and constant positive pressure ventilation with PEEP of up to 28 cm H2O was instituted. The patient survived and recovery appeared to be complete. Severe pulmonary edema is not a common finding in patients who have Endrin poisoning. The use of PEEP above 15 cm H2O is a controversial issue; however, we believe that it contributed significantly to the survival of our patient.
杀虫剂异狄氏剂是一种剧毒的氯代烃，可导致严重的中枢神经系统和呼吸系统紊乱。中毒后通常在24小时内死亡。一名19岁男性在摄入异狄氏剂后出现惊厥和严重肺水肿。对其进行气管插管，并采用持续正压通气，呼气末正压高达28 cm H2O。患者存活，且恢复似乎完全。严重肺水肿在异狄氏剂中毒患者中并不常见。使用呼气末正压超过15 cm H2O是一个有争议的问题；然而，我们认为这对我们患者的存活有显著贡献。
