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晕厥研究 25 年

Twenty-five years of research on syncope.

机构信息

Department of Cardiology, Karolinska University Hospital, Eugeniavägen 3, 171 76 Solna, Stockholm, Sweden.

Department of Medicine, Karolinska Institute, Solnavägen 1, 171 77 Solna, Stockholm, Sweden.

出版信息

Europace. 2023 Aug 25;25(8). doi: 10.1093/europace/euad163.

DOI:10.1093/europace/euad163
PMID:37622579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10450792/
Abstract

Over the last 25 years, the Europace journal has greatly contributed to dissemination of research and knowledge in the field of syncope. More than 400 manuscripts have been published in the journal. They undoubtedly improved our understanding of syncope. This symptom is now clearly differentiated from other forms of transient loss of consciousness. The critical role of vasodepression and/or cardioinhibition as final mechanisms of reflex syncope is emphasized. Current diagnostic approach sharply separates between cardiac and autonomic pathways. Physiologic insights have been translated, through rigorously designed clinical trials, into non-pharmacological or pharmacological interventions and interventional therapies. The following manuscript is intended to give the reader the current state of the art of knowledge of syncope by highlighting landmark contributions of the Europace journal.

摘要

在过去的 25 年里,《欧洲心脏起搏、电生理和心脏起搏杂志》(Europace)极大地促进了晕厥领域的研究和知识的传播。该期刊发表了超过 400 篇论文,无疑提高了我们对晕厥的认识。目前,这种症状已明显与其他形式的短暂意识丧失区分开来。目前强调的是血管舒张和/或心脏抑制作为反射性晕厥的最终机制的关键作用。当前的诊断方法通过严格设计的临床试验,将心脏和自主途径明显区分开来。通过严格设计的临床试验,生理见解已转化为非药物或药物干预和介入治疗。本手稿旨在通过强调《欧洲心脏起搏、电生理和心脏起搏杂志》的里程碑式贡献,为读者提供晕厥领域当前的知识现状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/97a0f4d28c35/euad163f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/1d5d319a0671/euad163_ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/ff5f807cfe0d/euad163f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/3e386860fa92/euad163f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/f64b0578a9aa/euad163f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/97a0f4d28c35/euad163f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/1d5d319a0671/euad163_ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/ff5f807cfe0d/euad163f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/3e386860fa92/euad163f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/f64b0578a9aa/euad163f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/10450792/97a0f4d28c35/euad163f4.jpg

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Age and sex differences in vasovagal syncope: triggers, clinical presentation, prodromal symptoms, and head-up tilt test results.血管迷走性晕厥的年龄和性别差异:触发因素、临床表现、前驱症状及直立倾斜试验结果。
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Clinical variables do not predict syncope in pacemaker patients with bifascicular block: a SPRITELY substudy.

本文引用的文献

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Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: the fast Italian protocol.舌下含服硝酸甘油增强的短时间直立倾斜试验在疑似血管迷走性晕厥中的应用:快速意大利方案。
Eur Heart J. 2023 Jul 14;44(27):2473-2479. doi: 10.1093/eurheartj/ehad322.
2
Autonomic control of ventricular function in health and disease: current state of the art.自主神经对心室功能在健康和疾病中的控制:当前的最新技术。
Clin Auton Res. 2023 Aug;33(4):491-517. doi: 10.1007/s10286-023-00948-8. Epub 2023 May 11.
3
Syncope Diagnosis at Referral to a Tertiary Syncope Unit: An in-Depth Analysis of the FAST II.
临床变量无法预测存在双分支阻滞的起搏器植入患者的晕厥情况:一项SPRITELY子研究。
Clin Auton Res. 2025 Jun 3. doi: 10.1007/s10286-025-01138-4.
4
Syncope and All-Cause Mortality in Heart Failure: A Propensity Score-Matched Analysis.心力衰竭中的晕厥与全因死亡率:一项倾向评分匹配分析
Mayo Clin Proc Innov Qual Outcomes. 2025 Apr 22;9(3):100620. doi: 10.1016/j.mayocpiqo.2025.100620. eCollection 2025 Jun.
5
A study on the therapeutic effect of zero-ray cardiac autonomic ganglion ablation on vasovagal syncope in a special occupational young population.零射线心脏自主神经节消融术对特殊职业青年人群血管迷走性晕厥治疗效果的研究
Front Cardiovasc Med. 2025 Apr 3;12:1537827. doi: 10.3389/fcvm.2025.1537827. eCollection 2025.
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Head-up tilt testing in older syncope patients: a systematic review.老年晕厥患者的头高位倾斜试验:一项系统评价
Age Ageing. 2025 Mar 28;54(4). doi: 10.1093/ageing/afaf086.
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A contemporary review of the head-up tilt test: Utility and limitations.头高位倾斜试验的当代综述:效用与局限性
Indian Heart J. 2025 May-Jun;77(3):243-251. doi: 10.1016/j.ihj.2025.03.014. Epub 2025 Apr 2.
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Pathophysiological aspects of carotid sinus massage.颈动脉窦按摩的病理生理方面。
Europace. 2025 Mar 28;27(4). doi: 10.1093/europace/euaf047.
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J Clin Med. 2025 Feb 7;14(4):1052. doi: 10.3390/jcm14041052.
转诊至三级晕厥诊疗单元时的晕厥诊断:FAST II的深入分析
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