• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

医护人员对青霉素过敏标签的态度。

Healthcare professionals' attitudes to penicillin allergy labels.

机构信息

Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital - Herlev and Gentofte Hospital.

UCSF Centre for Health Research, Copenhagen University Hospital - Rigshospitalet.

出版信息

Dan Med J. 2023 Aug 23;70(9):A03230180.

PMID:37622646
Abstract

INTRODUCTION

About 10% of hospital inpatients are labelled with penicillin allergy in their electronic medical record (EMR). However, allergy is confirmed in less than 10% of these records. Consequently, 90% of patients are treated with broad-spectrum antibiotics, contributing to antimicrobial resistance. We aimed to explore experiences and practices of healthcare professionals that may explain incorrect labelling of penicillin allergy in Denmark and elucidate any consequences hereof.

METHODS

An electronic survey was distributed to physicians and nurses in six hospital units in Copenhagen and via social media. The survey was active from 19 March to 1 May 2020. Data were assessed using descriptive statistics and by thematic analysis.

RESULTS

The response rate was 44.6%. The survey had 369 participants; 152 physicians and 217 nurses. Half of the physicians and one in every five nurses had experienced problems treating patients with a penicillin allergy label. Physicians reported limited trust in allergy labels, and labelling practices varied. The risk that patients may be truly allergic was the main reason for not removing labels (72%), and a precautionary principle was identified related to penicillin allergy labelling.

CONCLUSIONS

The penicillin allergy label is an independent factor of medication errors. Solutions to enhance patient safety may include education of physicians in allergy labelling, decision support, standardisation of the allergy registration in the various EMR systems used, and ideally also a national drug allergy register, which is accessible from all sectors.

FUNDING

None.

TRIAL REGISTRATION

Not relevant.

摘要

简介

大约 10%的住院患者在其电子病历(EMR)中被标记为青霉素过敏。然而,在这些记录中,不到 10%的患者被证实有过敏反应。因此,90%的患者接受了广谱抗生素治疗,导致了抗菌药物耐药性的产生。我们旨在探讨可能导致丹麦青霉素过敏错误标记的医护人员的经验和做法,并阐明由此产生的任何后果。

方法

我们向哥本哈根六家医院科室的医生和护士以及通过社交媒体分发了电子调查问卷。该调查于 2020 年 3 月 19 日至 5 月 1 日期间进行。我们使用描述性统计和主题分析来评估数据。

结果

回复率为 44.6%。调查共有 369 名参与者,其中包括 152 名医生和 217 名护士。一半的医生和五分之一的护士在治疗有青霉素过敏标签的患者时遇到了问题。医生报告说他们对过敏标签的信任有限,而且标签的使用做法也存在差异。不删除标签的主要原因是担心患者可能真的过敏(72%),并确定了与青霉素过敏标签相关的预防原则。

结论

青霉素过敏标签是药物错误的一个独立因素。增强患者安全的解决方案可能包括对医生进行过敏标签教育、决策支持、在使用的各种 EMR 系统中标准化过敏登记,以及理想情况下还应建立一个全国性的药物过敏登记系统,以便从所有部门都可以访问。

经费

无。

试验注册

不相关。

相似文献

1
Healthcare professionals' attitudes to penicillin allergy labels.医护人员对青霉素过敏标签的态度。
Dan Med J. 2023 Aug 23;70(9):A03230180.
2
Focus group study exploring the issues and the solutions to incorrect penicillin allergy-labelled patients: an antibiotic stewardship patient safety initiative.聚焦小组研究探索青霉素过敏标签错误患者的问题和解决方案:抗生素管理患者安全计划。
Eur J Hosp Pharm. 2021 Mar;28(2):71-75. doi: 10.1136/ejhpharm-2019-001863. Epub 2019 Jun 11.
3
Removal of incorrect penicillin allergy labels in a UK hospital.在英国一家医院去除错误的青霉素过敏标签。
Clin Microbiol Infect. 2023 Oct;29(10):1338.e1-1338.e4. doi: 10.1016/j.cmi.2023.06.024. Epub 2023 Jun 22.
4
DALES, Drug Allergy Labels in Elective Surgical patients: a prospective multicentre cross-sectional study of incidence, risks, and attitudes in penicillin de-labelling strategies.《选择性手术患者中的药物过敏标签:去青霉素标签策略中的发生率、风险和态度的前瞻性多中心横断面研究》。
Br J Anaesth. 2020 Dec;125(6):962-969. doi: 10.1016/j.bja.2020.07.048. Epub 2020 Aug 25.
5
Unconfirmed penicillin allergy labels in the paediatric outpatient setting: A call for research and quality improvement initiatives.儿科门诊环境中未经证实的青霉素过敏标签:呼吁开展研究和质量改进举措。
J Paediatr Child Health. 2021 May;57(5):607-610. doi: 10.1111/jpc.15445. Epub 2021 Mar 16.
6
The prevalence of suspected and challenge-verified penicillin allergy in a university hospital population.一所大学医院人群中疑似及经激发试验证实的青霉素过敏的患病率。
Basic Clin Pharmacol Toxicol. 2006 Apr;98(4):357-62. doi: 10.1111/j.1742-7843.2006.pto_230.x.
7
A multicentre observational study to investigate feasibility of a direct oral penicillin challenge in de-labelling 'low risk' patients with penicillin allergy by non-allergy healthcare professionals (SPACE study): Implications for healthcare systems.一项多中心观察性研究,旨在调查非过敏专业医护人员通过直接口服青霉素挑战来解除“低危”青霉素过敏患者标签(SPACE 研究)的可行性:对医疗保健系统的影响。
J Infect. 2024 Mar;88(3):106116. doi: 10.1016/j.jinf.2024.01.015. Epub 2024 Feb 6.
8
Recognizing the opportunity to directly de-label no-risk penicillin allergies in community pharmacy: a mystery shopper experience.识别直接消除社区药房中无风险青霉素过敏标签的机会:神秘顾客体验。
Int J Pharm Pract. 2024 Jul 4;32(4):267-273. doi: 10.1093/ijpp/riae020.
9
Barriers to paediatric penicillin allergy de-labelling in UK secondary care: a regional survey.英国二级医疗中儿童青霉素过敏重新认定的障碍:一项区域调查
Arch Dis Child. 2023 May;108(5):363-366. doi: 10.1136/archdischild-2022-324564. Epub 2022 Dec 19.
10
The challenge of de-labeling penicillin allergy.消除青霉素过敏标签的挑战。
Allergy. 2020 Feb;75(2):273-288. doi: 10.1111/all.13848. Epub 2019 May 26.

引用本文的文献

1
"What if the patient has a severe reaction, and it is my fault?" A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling.如果患者出现严重反应,那是我的错怎么办?一项探索青霉素过敏标签修正可持续实施因素的定性研究。
Antimicrob Resist Infect Control. 2024 Sep 2;13(1):97. doi: 10.1186/s13756-024-01456-8.