Waltzman S B, Cohen N L, Shapiro W H
Laryngoscope. 1986 Oct;96(10):1083-7. doi: 10.1288/00005537-198610000-00007.
A major concern regarding multichannel (multi-electrode) cochlear prosthesis usage has been the possibility of long-term deleterious physiological effects such as the degeneration of spiral ganglion cells, neuronal degeneration, and new bone formation. These effects, if present, would become evident in the deterioration of hearing sensation and performance of the cochlear implant recipient on a battery of audiologic tests. To date, five patients using the Australian multi-electrode multichannel cochlear implant have undergone a 1-year evaluation of the device. The assessment includes a check of electrical threshold and comfort levels for each electrode, sound field pure tone and speech thresholds, the MAC battery, vowel and consonant recognition tests, and speech tracking tasks. All results were compared to those obtained postoperatively following stimulation and a 3-month training period. Results to date have shown no deterioration in implant functioning in all patients tested. Periodic extensive monitoring of all implant recipients is advocated in order to evaluate the possibility of long-term effects.
关于多通道（多电极）人工耳蜗使用的一个主要担忧是长期有害生理影响的可能性，如螺旋神经节细胞退化、神经元变性和新骨形成。如果存在这些影响，在一系列听力学测试中，人工耳蜗植入者的听觉感受和表现恶化时就会变得明显。迄今为止，五名使用澳大利亚多电极多通道人工耳蜗的患者已对该设备进行了为期一年的评估。评估包括检查每个电极的电阈值和舒适度水平、声场纯音和言语阈值、MAC电池、元音和辅音识别测试以及言语跟踪任务。所有结果都与刺激后及3个月训练期后的术后结果进行了比较。迄今为止的结果表明，所有测试患者的植入功能均未恶化。提倡对所有植入者进行定期广泛监测，以评估长期影响的可能性。
