Cornblath D R
Muscle Nerve. 1986 Sep;9(7):606-11. doi: 10.1002/mus.880090705.
Disorders of neuromuscular transmission in infants and children can be divided into two groups. The first group includes conditions similar to those seen in adults: autoimmune myasthenia gravis, Lambert-Eaton myasthenic syndrome, and botulism. The second includes several disorders that are unique to this age group, such as the congenital myasthenias and infantile botulism. This review discusses the diseases of neuromuscular transmission found in the pediatric population, with emphasis on electrodiagnosis. The distinctive clinical and electrophysiologic features allow the clinician to identify these illnesses correctly, so that appropriate treatment can be instituted or further specialized investigation can be undertaken.
婴幼儿和儿童的神经肌肉传递障碍可分为两组。第一组包括与成人相似的病症:自身免疫性重症肌无力、兰伯特-伊顿肌无力综合征和肉毒中毒。第二组包括该年龄组特有的几种病症,如先天性肌无力和婴儿肉毒中毒。本综述讨论了儿科人群中发现的神经肌肉传递疾病,重点是电诊断。独特的临床和电生理特征使临床医生能够正确识别这些疾病,从而可以采取适当的治疗措施或进行进一步的专业调查。