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婴幼儿神经肌肉传递障碍

Disorders of neuromuscular transmission in infants and children.

作者信息

Cornblath D R

出版信息

Muscle Nerve. 1986 Sep;9(7):606-11. doi: 10.1002/mus.880090705.

DOI:10.1002/mus.880090705
PMID:3762582
Abstract

Disorders of neuromuscular transmission in infants and children can be divided into two groups. The first group includes conditions similar to those seen in adults: autoimmune myasthenia gravis, Lambert-Eaton myasthenic syndrome, and botulism. The second includes several disorders that are unique to this age group, such as the congenital myasthenias and infantile botulism. This review discusses the diseases of neuromuscular transmission found in the pediatric population, with emphasis on electrodiagnosis. The distinctive clinical and electrophysiologic features allow the clinician to identify these illnesses correctly, so that appropriate treatment can be instituted or further specialized investigation can be undertaken.

摘要

婴幼儿和儿童的神经肌肉传递障碍可分为两组。第一组包括与成人相似的病症:自身免疫性重症肌无力、兰伯特-伊顿肌无力综合征和肉毒中毒。第二组包括该年龄组特有的几种病症,如先天性肌无力和婴儿肉毒中毒。本综述讨论了儿科人群中发现的神经肌肉传递疾病,重点是电诊断。独特的临床和电生理特征使临床医生能够正确识别这些疾病,从而可以采取适当的治疗措施或进行进一步的专业调查。

相似文献

1
Disorders of neuromuscular transmission in infants and children.婴幼儿神经肌肉传递障碍
Muscle Nerve. 1986 Sep;9(7):606-11. doi: 10.1002/mus.880090705.
2
Electrodiagnostic evaluation of patients with myasthenia gravis and related disorders.
Neurol Clin. 1985 Aug;3(3):557-72.
3
Pearls and pitfalls in the diagnosis and management of neuromuscular junction disorders.神经肌肉接头疾病诊断与管理中的要点与陷阱
Semin Neurol. 2001 Dec;21(4):425-40. doi: 10.1055/s-2001-19414.
4
[Lambert-Eaton syndrome and myasthenia. Nosologic discussion].[兰伯特-伊顿综合征与重症肌无力。疾病分类学讨论]
Sem Hop. 1984 Jan 12;60(1):43-5.
5
Update on the evaluation and therapy of autoimmune neuromuscular junction disorders.自身免疫性神经肌肉接头疾病的评估与治疗进展
Phys Med Rehabil Clin N Am. 2001 May;12(2):381-97.
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Clinical neurophysiology of disorders of the neuromuscular junction.神经肌肉接头疾病的临床神经生理学
J Clin Neurophysiol. 1993 Apr;10(2):167-80. doi: 10.1097/00004691-199304000-00004.
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A diagnostic and management dilemma: combined paraneoplastic myasthenia gravis and Lambert-Eaton myasthenic syndrome presenting as acute respiratory failure.一个诊断与管理的难题:合并副肿瘤性重症肌无力和兰伯特-伊顿肌无力综合征并表现为急性呼吸衰竭
Neurologist. 2006 Nov;12(6):322-6. doi: 10.1097/01.nrl.0000250949.88356.22.
8
[Immunologic aspects of disorders of neuromuscular transmission. 2. Experimental autoimmune myasthenia gravis and the Lambert-Eaton myasthenic syndrome].[神经肌肉传递障碍的免疫学方面。2. 实验性自身免疫性重症肌无力和兰伯特-伊顿肌无力综合征]
Lijec Vjesn. 1994 May-Jun;116(5-6):158-61.
9
Electrodiagnosis of disorders of neuromuscular transmission.
Ann N Y Acad Sci. 1998 May 13;841:696-711. doi: 10.1111/j.1749-6632.1998.tb11005.x.
10
[Usefulness of electromyography in diagnostics of the neuro-muscular diseases].[肌电图在神经肌肉疾病诊断中的应用价值]
Przegl Lek. 2009;66(11):913-9.

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