马源性自身条件血清和自身蛋白溶液。

Equine Autologous Conditioned Serum and Autologous Protein Solution.

机构信息

Clinical Studies-New Bolton Center, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA.

出版信息

Vet Clin North Am Equine Pract. 2023 Dec;39(3):443-451. doi: 10.1016/j.cveq.2023.07.002. Epub 2023 Aug 23.

DOI:10.1016/j.cveq.2023.07.002

Abstract

Orthobiologics are used with increasing frequency in equine musculoskeletal disease to improve the quality of the repair tissue and prevent reinjury. Autologous blood-based products, or hemoderivatives, are made by processing the patient's blood using different systems to produce a final therapeutic product. Autologous conditioned serum (ACS) and autologous protein solution (APS) are commonly used to treat joint disorders and can also be used treat tendon and ligament injuries. Hemoderivatives contain increased concentrations of anti-inflammatory and immunomodulatory cytokines, and growth factors that help direct tissue healing and repair. The specifics of ACS and APS for treatment of musculoskeletal injuries are discussed.

摘要

矫形生物制剂在马属动物肌肉骨骼疾病中的应用日益增多，以改善修复组织的质量并预防再损伤。自体血液制品，或血液衍生物，是通过使用不同的系统处理患者的血液来制备最终的治疗产品。自体条件血清（ACS）和自体蛋白溶液（APS）常用于治疗关节疾病，也可用于治疗肌腱和韧带损伤。血液衍生物含有更高浓度的抗炎和免疫调节细胞因子和生长因子，有助于指导组织愈合和修复。本文讨论了 ACS 和 APS 治疗肌肉骨骼损伤的具体情况。