The BioActives Lab, Center for Desert Agriculture, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Plant Science Program, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Biomolecules. 2023 Aug 1;13(8):1206. doi: 10.3390/biom13081206.
The apocarotenoid zaxinone is a recently discovered regulatory metabolite required for proper rice growth and development. In addition, zaxinone and its two mimics (MiZax3 and MiZax5) were shown to have a remarkable growth-promoting activity on crops and a capability to reduce infestation by the root parasitic plant through decreasing strigolactone (SL) production, suggesting their potential for application in agriculture and horticulture. In the present study, we developed a new series of MiZax via structural modification of the two potent zaxinone mimics (MiZax3 and MiZax5) and evaluated their effect on plant growth and infestation. In general, the structural modifications to MiZax3 and MiZax5 did not additionally improve their overall performance but caused an increase in certain activities. In conclusion, MiZax5 and especially MiZax3 remain the likely most efficient zaxinone mimics for controlling infestation.
类胡萝卜素降解产物玉米黄质酮是一种最近发现的调控代谢物，对于水稻的正常生长和发育是必需的。此外，玉米黄质酮及其两种类似物（MiZax3 和 MiZax5）对作物具有显著的促生长活性，并能够通过减少独脚金内酯（SL）的产生来减少寄生性植物的侵害，这表明它们在农业和园艺领域具有应用潜力。在本研究中，我们通过对两种强效玉米黄质酮类似物（MiZax3 和 MiZax5）进行结构修饰，开发了一系列新的 MiZax，并评估了它们对植物生长和侵害的影响。总的来说，对 MiZax3 和 MiZax5 的结构修饰并没有进一步提高它们的整体性能，反而导致某些活性增加。总之，MiZax5 特别是 MiZax3 仍然是控制侵害最有效的玉米黄质酮类似物。
