Masarone Daniele, Kittleson Michelle M, Falco Luigi, Martucci Maria L, Catapano Dario, Brescia Benedetta, Petraio Andrea, De Feo Marisa, Pacileo Giuseppe
Heart Failure Unit, Department of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Hospital, Los Angeles, CA 90048, USA.
J Clin Med. 2023 Aug 10;12(16):5217. doi: 10.3390/jcm12165217.
Cardiac transplantation represents the gold standard of treatment for selected patients with advanced heart failure who have poor functional capacity and prognosis despite guideline-directed medical therapy and device-based therapy. Proper patient selection and appropriate referral of patients to centers for the treatment of advanced heart failure are the first but decisive steps for screening patients eligible for cardiac transplantation. The eligibility and the decision to list for cardiac transplantation, even for patients with relative contraindications, are based on a multidisciplinary evaluation of a transplant team. This review will discuss the practical indications, the process of patient eligibility for cardiac transplantation, the principle of donor selection, as well as the surgical technique.
心脏移植是某些晚期心力衰竭患者的治疗金标准，这些患者尽管接受了指南指导的药物治疗和基于器械的治疗，但功能能力和预后仍较差。正确选择患者并将其适当地转诊至晚期心力衰竭治疗中心是筛选适合心脏移植患者的首要且决定性步骤。心脏移植的资格以及即使是有相对禁忌症的患者列入移植名单的决定，均基于移植团队的多学科评估。本综述将讨论心脏移植的实际适应症、患者符合移植资格的流程、供体选择原则以及手术技术。
