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非惊厥性全身性癫痫持续状态:临床特征、神经心理学测试及长期随访

Nonconvulsive generalized status epilepticus: clinical features, neuropsychological testing, and long-term follow-up.

作者信息

Guberman A, Cantu-Reyna G, Stuss D, Broughton R

出版信息

Neurology. 1986 Oct;36(10):1284-91. doi: 10.1212/wnl.36.10.1284.

DOI:10.1212/wnl.36.10.1284
PMID:3762932
Abstract

We studied 13 episodes of nonconvulsive generalized status epilepticus (NGS) in 10 adults. The syndrome may start in middle or late life and is often mistaken for psychiatric disorders. Some patients have shown good retention of language abilities, except for reduced fluency, despite impairment in other higher functions. In most patients, the syndrome recurs for several years despite anticonvulsant therapy. Transitional cases of NGS with lateralizing EEG features exist, and some cases are probably due to secondary generalization from a temporal or frontal focus.

摘要

我们研究了10名成年人中的13例非惊厥性全面性癫痫持续状态(NGS)发作情况。该综合征可能始于中年或晚年,常被误诊为精神障碍。尽管其他高级功能受损,但一些患者除了流利度下降外,语言能力保留良好。在大多数患者中,尽管进行了抗惊厥治疗,该综合征仍会复发数年。存在具有脑电图定位特征的NGS过渡病例,有些病例可能是由于颞叶或额叶病灶继发全面性发作所致。

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