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男性肥胖的临床及治疗意义

Clinical and Therapeutic Implications of Male Obesity.

作者信息

Lenart-Lipińska Monika, Łuniewski Michał, Szydełko Joanna, Matyjaszek-Matuszek Beata

机构信息

Department of Endocrinology, Diabetology, and Metabolic Diseases, Medical University of Lublin, 20-954 Lublin, Poland.

出版信息

J Clin Med. 2023 Aug 17;12(16):5354. doi: 10.3390/jcm12165354.

DOI:10.3390/jcm12165354
PMID:37629396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10455727/
Abstract

The prevalence of obesity, a disorder linked to numerous comorbidities and metabolic complications, has recently increased dramatically worldwide and is highly prevalent in men, even at a young age. Compared to female patients, men with obesity more frequently have delayed diagnosis, higher severity of obesity, increased mortality rate, and only a minority of obese male patients are successfully treated, including with bariatric surgery. The aim of this review was to present the current state of knowledge about the clinical and therapeutic implications of obesity diagnosed in males.

摘要

肥胖是一种与多种合并症和代谢并发症相关的疾病,最近在全球范围内急剧增加,在男性中也非常普遍,甚至在年轻时也是如此。与女性患者相比,肥胖男性患者的诊断往往延迟,肥胖程度更高,死亡率增加,而且只有少数肥胖男性患者得到成功治疗,包括接受减肥手术。这篇综述的目的是介绍目前关于男性肥胖的临床和治疗意义的知识现状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f0/10455727/ead2165b7f9a/jcm-12-05354-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f0/10455727/ead2165b7f9a/jcm-12-05354-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87f0/10455727/ead2165b7f9a/jcm-12-05354-g001.jpg

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本文引用的文献

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JAMA. 2023 Jul 25;330(4):306. doi: 10.1001/jama.2023.12055.
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Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.三重激素受体激动剂 Retatrutide 治疗肥胖症的 2 期临床试验
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Effects of sodium glucose cotransporter 2 inhibitors and pioglitazone on FIB-4 index in metabolic-associated fatty liver disease.
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Int J Mol Sci. 2021 Oct 27;22(21):11629. doi: 10.3390/ijms222111629.
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J Gastroenterol Hepatol. 2022 Jan;37(1):7-14. doi: 10.1111/jgh.15713. Epub 2021 Nov 3.
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