Skin Center-Dermo Aesthetic Laser Centers, 67051 Avezzano, Italy.
Roma Clinic, Baghdad 10001, Iraq.
Medicina (Kaunas). 2023 Jul 31;59(8):1406. doi: 10.3390/medicina59081406.
Dermal fillers for soft tissue for the treatment of face sagging, volume loss, and wrinkles have become popular among patients of all ages and ethnicities, and their use is becoming increasingly widespread. Aim: the goal of this study was to evaluate the effectiveness and safety of a micro-pulsed, 1444 nm Nd:YAG laser on dermal filler complications, in particular on granuloma management. A subcutaneous, 1444 nm Nd:YAG laser was used on five female patients (range age 52-68 years) with hyaluronic filler granulomas located on the face (two on the cheek area and three on the lips); three patients had self-injected the filler, buying it online. Before and after the therapy, the patients received a skin ultrasound to determine the form and location of the granulomas and to determine if there had been a full or partial resolution. During this study, all possible adverse effects at the treatment site were monitored. The 5-point Global Aesthetic Improvement Scale (GAIS) (0 point-no change; 1 point-25%, mild improvement; 2 points-50%, moderate improvement; 3 points-75%, good improvement; 4 points-100%, excellent improvement) was recorded at a 3-month follow-up. good results were obtained in the treatment of filler granulomas with the intralesional 1444 nm laser, even if just a single treatment was performed (one intervention was effective for curing granulomas up to 5 mm in diameter). Three patients were satisfied with excellent improvement, and two patients experienced good improvement. The results are functional and aesthetically satisfying, as shown by photographic assessment. At the last follow-up, the granuloma had reduced or completely disappeared in all cases, and no infections, burns, scarring or fibrosis, episodes of severe bleeding, or other serious adverse effects had been reported. All subjects tolerated the post-treatment period well. Our findings showed that granuloma treatment with an intralesional 1444 nm Nd:YAG laser is a minimally invasive, easy, fast, efficient, and low-risk procedure.
用于治疗面部下垂、体积损失和皱纹的软组织填充剂已在各个年龄段和不同种族的患者中广受欢迎，其应用也越来越广泛。目的：本研究旨在评估微脉冲、1444nmNd:YAG 激光治疗皮肤填充物并发症，特别是肉芽肿管理的有效性和安全性。在五名女性患者（年龄 52-68 岁）中，采用皮下 1444nmNd:YAG 激光治疗位于面部的透明质酸填充物肉芽肿（脸颊区域两个，嘴唇三个）；三名患者自行注射填充物，从网上购买。治疗前后，患者均接受皮肤超声检查，以确定肉芽肿的形态和位置，并确定是否完全或部分缓解。在本研究中，监测了治疗部位的所有可能的不良反应。在 3 个月的随访中，使用 5 分整体美学改善量表（GAIS）（0 分无变化；1 分 25%，轻度改善；2 分 50%，中度改善；3 分 75%，明显改善；4 分 100%，极好改善）进行记录。在治疗填充物肉芽肿方面，1444nm 激光的皮内注射取得了良好的效果，即使只进行了一次治疗（一次干预对直径达 5mm 的肉芽肿有效）。三名患者对极好的改善效果满意，两名患者对良好的改善效果满意。照片评估显示，结果在功能和美学上均令人满意。最后一次随访时，所有病例的肉芽肿均减少或完全消失，未报告感染、烧伤、瘢痕或纤维化、严重出血发作或其他严重不良反应。所有患者均能很好地耐受治疗后的时期。我们的研究结果表明，1444nmNd:YAG 激光皮内注射治疗肉芽肿是一种微创、简便、快速、高效且低风险的方法。
