Vitamin D and Its Association with Prevalence and Eradication: A Comprehensive Review.

Taking into account previous data that sustain a relationship between vitamin D deficiency and higher infection positivity rates, this review aims to assess the influence of vitamin D deficiency and/or insufficiency upon the prevalence of infection and its eradication success. Three major databases were searched for articles that analyzed a relationship between vitamin D status and infection. The literature search retrieved a total of 37 reports, after the article selection process. Hypovitaminosis D emerged as a potential risk factor for infection, given the higher prevalence of vitamin D deficiency and/or insufficiency among -positive subjects. Furthermore, the same type of micronutrient deficiency has been directly linked to eradication failure. An inverse linear relationship between vitamin D status and gastric cancer risk exists, but the additional involvement of in this correlation is still in question. The potential benefit of oral supplements in enhancing the success of classical therapeutic regimens of still requires future research. Future population-based studies from larger geographical areas are warranted to address this subject in more depth.