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纽约市用于提供替考韦瑞马特治疗猴痘感染的远程医疗就诊模式的实施及早期结果

Implementation and early outcomes of a telehealth visit model to deliver tecovirimat for mpox infection in New York City.

作者信息

Chan Justin, DiTullio David J, Pagan Pirallo Patricia, Foote Mary, Knutsen Dorothy, Kottkamp Angelica Cifuentes, McPherson Tristan D, Mukherjee Vikramjit, Pitts Robert, Wallach Andrew, Wong Marcia, Mazo Dana, Mgbako Ofole

机构信息

NYC Health + Hospitals/Bellevue, New York, NY, USA.

NYU Grossman School of Medicine, New York, NY, USA.

出版信息

J Telemed Telecare. 2025 May;31(4):534-539. doi: 10.1177/1357633X231194796. Epub 2023 Aug 25.

DOI:10.1177/1357633X231194796
PMID:37632124
Abstract

The 2022 mpox outbreak in New York City posed challenges to rapidly scaling up treatment capacity. We describe a telehealth treatment model launched during this outbreak that facilitated healthcare provider treatment capacity, and was able to adhere to a Centers for Disease Control and Prevention (CDC)-sponsored expanded access investigational new drug (EA-IND) protocol for tecovirimat. Sixty-nine patients were evaluated and prescribed tecovirimat for mpox through telehealth visits at NYC Health + Hospitals/Bellevue and NYU Langone Health from June to August 2022. Thirty-two (46.4%) were previously diagnosed with HIV. Forty-four (63.8%) reported full recovery, with the remainder lost to follow-up. Most patients ( = 60, 87.0%) attended at least one follow-up visit (either in person or through telehealth) after starting treatment. We observed favorable treatment outcomes, with no serious adverse events, hospitalizations, or deaths related to mpox. While equitable access to telehealth remains a limitation that needs to be addressed, this telehealth model enabled a rapid scale-up of tecovirimat prescription during the mpox outbreak, and should be considered as an important tool used to respond to future infectious disease outbreaks.

摘要

2022年纽约市的猴痘疫情给迅速扩大治疗能力带来了挑战。我们描述了在此次疫情期间推出的一种远程医疗治疗模式,该模式提高了医疗服务提供者的治疗能力,并能够遵循美国疾病控制与预防中心(CDC)赞助的关于tecovirimat的扩大准入研究性新药(EA-IND)方案。2022年6月至8月期间,在纽约市卫生与医院管理局/贝莱维医院以及纽约大学朗格尼健康中心,通过远程医疗问诊对69名猴痘患者进行了评估并开具了tecovirimat处方。其中32人(46.4%)此前被诊断出感染艾滋病毒。44人(63.8%)报告已完全康复,其余患者失访。大多数患者(n = 60,87.0%)在开始治疗后至少进行了一次随访(亲自就诊或通过远程医疗)。我们观察到了良好的治疗效果,没有出现与猴痘相关的严重不良事件、住院或死亡情况。虽然远程医疗的公平可及性仍是一个需要解决的限制因素,但这种远程医疗模式在猴痘疫情期间实现了tecovirimat处方的快速扩大,应被视为应对未来传染病疫情的一项重要工具。

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Implementation and early outcomes of a telehealth visit model to deliver tecovirimat for mpox infection in New York City.纽约市用于提供替考韦瑞马特治疗猴痘感染的远程医疗就诊模式的实施及早期结果
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