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71 岁女性法洛四联症未修复:病例报告及文献复习。

Unrepaired tetralogy of Fallot in a 71 years old woman: A case report and review of the literature.

机构信息

Atherosclerosis Prevention Research Center, Echocardiography laboratory, Cardiovascular Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Echocardiography. 2023 Nov;40(11):1269-1275. doi: 10.1111/echo.15677. Epub 2023 Aug 25.

Abstract

Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease (CHD) in infants. The four components that constitute ToF are an overriding aorta over the crest of the interventricular septum, obstruction in the right ventricular outflow tract, right ventricular hypertrophy, and a typically large non-restricted ventricular septal defect. ToF may also be associated with other extracardiac abnormalities, including patent ductus arteriosus or multiple aortopulmonary collateral arteries, which can impact the patient's survival. Patients with unoperated ToF rarely reach adulthood, and it is extremely rare to discover undiagnosed ToF in individuals over 60 years old. In this report, we describe an unusual case of a woman with unrepaired ToF who survived until the age of 71. She was fairly asymptomatic until the 7th decade of her life and complained only of dyspnea on exertion. The patient declined corrective cardiac surgery and preferred conservative management.

摘要

法洛四联症(ToF)是婴儿期最常见的发绀型先天性心脏病(CHD)。ToF 的四个组成部分是:主动脉瓣骑跨于室间隔之上,右心室流出道梗阻,右心室肥厚,以及通常较大的非限制性室间隔缺损。ToF 也可能与其他心脏外异常相关,包括动脉导管未闭或多发性体肺侧支动脉,这可能影响患者的生存。未经手术的 ToF 患者很少能活到成年,在 60 岁以上的人群中发现未经诊断的 ToF 极为罕见。在本报告中,我们描述了一例罕见的未修复 ToF 女性患者,她活到了 71 岁。她在生命的第 7 个十年几乎没有症状,仅在运动时出现呼吸困难。患者拒绝进行矫正性心脏手术,选择保守治疗。

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