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59 岁未手术法洛四联症患者的治疗。

Management of Unoperated Tetralogy of Fallot in a 59-Year-Old Patient.

机构信息

Riverside University Health Systems, Moreno Valley, CA, USA.

Loma Linda University Medical Center, Loma Linda, CA, USA.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620926908. doi: 10.1177/2324709620926908.

DOI:10.1177/2324709620926908
PMID:32462941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7273539/
Abstract

Tetralogy of Fallot is the most common cyanotic congenital heart defect consisting of an overriding aorta, right ventricular outflow obstruction, ventricular septal defect, and right ventricular hypertrophy. Without surgical management, approximately only 3% of patients survive past the age of 40 years. Cases of unoperated patients reaching adulthood have been reported; however, few studies describe treatment guidelines for surgical or therapeutic management. In this article, we report the case of a 59-year-old Hispanic male with unoperated tetralogy of Fallot presenting to our cardiology clinic for initial workup and management.

摘要

法洛四联症是最常见的发绀型先天性心脏缺陷,由主动脉骑跨、右心室流出道梗阻、室间隔缺损和右心室肥厚组成。未经手术治疗,约只有 3%的患者能存活至 40 岁以上。有报道称未经手术的成年患者病例,但很少有研究描述手术或治疗管理的治疗指南。本文报告了一例 59 岁的西班牙裔男性,患有未经手术治疗的法洛四联症,因初始检查和治疗而到我院心内科就诊。

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Management of Unoperated Tetralogy of Fallot in a 59-Year-Old Patient.59 岁未手术法洛四联症患者的治疗。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620926908. doi: 10.1177/2324709620926908.
2
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Clinical and morphologic features of perimembranous ventricular septal defect with overriding of the aorta--the so-called Eisenmenger ventricular septal defect. A study making comparisons with tetralogy of Fallot and perimembranous ventricular defect without aortic overriding.主动脉骑跨的膜周部室间隔缺损的临床和形态学特征——即所谓的艾森曼格室间隔缺损。一项与法洛四联症和无主动脉骑跨的膜周部室间隔缺损进行比较的研究。
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Tetralogy of Fallot.法洛四联症
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An extraordinary survival at the age of 67 years in an unoperated case tetralogy of Fallot presenting as systemic hypertension despite RV dysfunction.一名67岁未经手术治疗的法洛四联症患者,尽管存在右心室功能障碍,但以系统性高血压为表现,却实现了非凡的生存。
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Cureus. 2024 Jan 26;16(1):e52987. doi: 10.7759/cureus.52987. eCollection 2024 Jan.
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The Unrepaired Tetralogy of Fallot: A Tale of Delayed Presentation and Limited Access to Care.

本文引用的文献

1
An extraordinary survival at the age of 67 years in an unoperated case tetralogy of Fallot presenting as systemic hypertension despite RV dysfunction.一名67岁未经手术治疗的法洛四联症患者,尽管存在右心室功能障碍,但以系统性高血压为表现,却实现了非凡的生存。
BMJ Case Rep. 2014 Jan 28;2014:bcr2013202647. doi: 10.1136/bcr-2013-202647.
2
Survival to the age of 87 years in a woman with unoperated tetralogy of Fallot.一名未接受手术治疗的法洛四联症女性活到了87岁。
J Radiol Case Rep. 2009;3(8):14-7. doi: 10.3941/jrcr.v3i8.264. Epub 2009 Aug 1.
3
Tetralogy of fallot repair in patients 40 years or older.
未经修复的法洛四联症:延迟就诊与医疗资源受限的故事
Cureus. 2024 Jan 16;16(1):e52407. doi: 10.7759/cureus.52407. eCollection 2024 Jan.
4
The Case of a 44-Year-Old Survivor of Unrepaired Tetralogy of Fallot, Right Aortic Arch and Abdominal Aortopulmonary Collateral Vessels.法洛四联症未修复、右主动脉弓和腹主动脉肺侧支血管患者 44 岁生存案例。
Medicina (Kaunas). 2022 Jul 28;58(8):1011. doi: 10.3390/medicina58081011.
法洛四联症修复术在 40 岁及以上患者中的应用。
Mayo Clin Proc. 2010 Dec;85(12):1090-4. doi: 10.4065/mcp.2010.0286.
4
Unoperated tetralogy of Fallot in a 68-year-old patient.一名68岁法洛四联症未手术患者。
Turk Kardiyol Dern Ars. 2008 Apr;36(3):175-7.
5
Unoperated tetralogy of Fallot: case report of a natural survivor who died in his 73rd year; is it ever too late to operate?未经手术治疗的法洛四联症:一名活到73岁的自然存活者的病例报告;手术是否永远都为时已晚?
Postgrad Med J. 2005 Feb;81(952):133-4. doi: 10.1136/pgmj.2004.020172.
6
What is the optimal age for repair of tetralogy of Fallot?法洛四联症修复的最佳年龄是多少?
Circulation. 2000 Nov 7;102(19 Suppl 3):III123-9. doi: 10.1161/01.cir.102.suppl_3.iii-123.
7
Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot.法洛四联症手术修复患者的长期预后
N Engl J Med. 1993 Aug 26;329(9):593-9. doi: 10.1056/NEJM199308263290901.
8
Landmark article May 19, 1945: The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia. By Alfred Blalock and Helen B. Taussig.里程碑文章,1945年5月19日:《伴有肺动脉狭窄或肺动脉闭锁的心脏畸形的外科治疗》。作者:阿尔弗雷德·布莱洛克和海伦·B·陶西格。
JAMA. 1984 Apr 27;251(16):2123-38. doi: 10.1001/jama.251.16.2123.
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Total correction of tetralogy of Fallot at age 40 years and older: long-term follow-up.40岁及以上法洛四联症的完全矫正:长期随访
J Am Coll Cardiol. 1985 Jan;5(1):40-4. doi: 10.1016/s0735-1097(85)80083-8.
10
Life expectancy without surgery in tetralogy of Fallot.法洛四联症未经手术治疗的预期寿命。
Am J Cardiol. 1978 Sep;42(3):458-66. doi: 10.1016/0002-9149(78)90941-4.