Division of Urology, UConn Health, Farmington, Connecticut, USA.
University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Can J Urol. 2023 Aug;30(4):11613-11618.
To evaluate patient preference for sperm disposition in case of death based on demographic factors and infertility etiology.
This retrospective cohort study was performed at a university hospital-affiliated fertility center. Charts of 550 men undergoing cryopreservation for assisted reproductive technologies (ART) between 2016-2019 were reviewed to create a descriptive dataset. Patients previously signed consent forms stating their preference for sperm transfer to their partner or disposal in the event of their subsequent death. Patients undergoing sperm cryopreservation for the purpose of ART were analyzed to assess associations between demographic characteristics and etiology of infertility and their choice to either transfer sperm to their partner or discard.
A total of 84.9% (342/403) of patients included in final analyses elected to transfer their sperm to their partner in the event of their death. Factors associated with a significantly increased likelihood to transfer versus discard included a male-factor infertility diagnosis compared to female-factor infertility diagnosis (transfer rate 89.3% vs. 79.9%; p = .022) and commercial insurance coverage versus non-commercial/no insurance coverage (transfer rate 86.3% vs. 75.0%, p = .029). No significant differences relating to age, race/ethnicity, occupation classification, marital status or duration of marriage, or prior paternity were found.
A majority of male patients seeking sperm cryopreservation for ART elected to transfer their sperm to their partner if future death should occur. There does not appear to be a clear factor that would impact this decision based on demographic characteristics.
评估基于人口统计学因素和不孕病因的患者在死亡情况下对精子处置的偏好。
这项回顾性队列研究在一家大学医院附属的生育中心进行。对 2016-2019 年间进行辅助生殖技术(ART)冷冻保存的 550 名男性患者的图表进行了回顾,以创建描述性数据集。患者之前签署了同意书,表明他们在随后死亡的情况下,将精子转移给伴侣或处置的偏好。对接受精子冷冻保存以进行 ART 的患者进行分析,以评估人口统计学特征和不孕病因与其选择将精子转移给伴侣或丢弃之间的关联。
最终分析中共有 84.9%(342/403)的患者选择在死亡时将精子转移给伴侣。与丢弃相比,显著增加转移可能性的因素包括男性因素不孕诊断而不是女性因素不孕诊断(转移率 89.3%对 79.9%;p =.022)和商业保险覆盖而不是非商业/无保险覆盖(转移率 86.3%对 75.0%,p =.029)。未发现与年龄、种族/民族、职业分类、婚姻状况或婚姻持续时间或先前亲权相关的显著差异。
大多数寻求 ART 精子冷冻保存的男性患者如果未来死亡,会选择将精子转移给伴侣。根据人口统计学特征,似乎没有一个明确的因素会影响这一决定。