Department of Obstetrics and Gynecology Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.
J Obstet Gynaecol Can. 2023 Dec;45(12):102198. doi: 10.1016/j.jogc.2023.102198. Epub 2023 Aug 25.
Treatment options for cases of pelvic organ prolapse still lead to the use of a pessary rather than a surgical method. Additional therapy is needed to help treat or prevent pelvic organ prolapse. Vitamin D deficiency has consistently been associated with decreased muscle function, so it is assumed that it will affect the pelvic floor muscles. This paper systematically explores the differences between 25-hydroxyvitamin D levels in patients with pelvic organ prolapse and non-pelvic organ prolapse.
A systematic review was conducted through the PubMed, Google Scholar, Cochrane Library, and ScienceDirect databases using relevant keywords. Articles published in the last 10 years-from 2012 to 2022-that were written in English, that discuss the status or effect of vitamin D on pelvic organ prolapse, and that focus on 25 OH-vitamin D were included in the review.
In total, 717 articles were filtered but 8 articles met the criteria. A total of 1339 women with prolapse and without prolapse with ages ranging from 20 years to 78 years were included in the study. The studies found did not use the same standard threshold in determining deficiency status. Most studies have found that there are lower levels of vitamin D in women who have had pelvic organ prolapse. A total of 7 of 8 studies confirmed the comparison of vitamin D-25OH levels in women with pelvic organ prolapse and without pelvic organ prolapse at P < 0.05.
There are differences between 25-hydroxyvitamin D levels in patients with pelvic organ prolapse and non-pelvic organ prolapse.
对于盆腔器官脱垂病例，治疗选择仍倾向于使用子宫托而非手术方法。需要额外的治疗来帮助治疗或预防盆腔器官脱垂。维生素 D 缺乏与肌肉功能下降密切相关，因此可以假设它会影响盆底肌肉。本文系统地探讨了盆腔器官脱垂患者和非盆腔器官脱垂患者 25-羟维生素 D 水平的差异。
通过 PubMed、Google Scholar、Cochrane Library 和 ScienceDirect 数据库，使用相关关键词进行了系统评价。纳入的文章为 2012 年至 2022 年期间发表的、以英文撰写的、讨论维生素 D 对盆腔器官脱垂状况或影响的文章，且重点关注 25-羟维生素 D。
共筛选出 717 篇文章，但有 8 篇符合标准。共有 1339 名患有脱垂和无脱垂的女性纳入研究，年龄在 20 岁至 78 岁之间。这些研究没有使用相同的标准阈值来确定缺乏状态。大多数研究发现，患有盆腔器官脱垂的女性维生素 D 水平较低。8 项研究中有 7 项证实了患有和不患有盆腔器官脱垂的女性 25-羟维生素 D 水平的比较差异具有统计学意义（P<0.05）。
盆腔器官脱垂患者与非盆腔器官脱垂患者的 25-羟维生素 D 水平存在差异。
