Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-Machi, Kanazawa, Ishikawa, 920-8641, Japan.
Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, 920-0942, Japan.
BMC Musculoskelet Disord. 2023 Aug 26;24(1):680. doi: 10.1186/s12891-023-06807-x.
Whether the medial meniscus morphology and movement occur under upright loading conditions in early knee osteoarthritis (OA) or medial meniscus posterior root tear (MMPRT) remains unknown. This study aimed to evaluate the medial and anteroposterior extrusion of the medial meniscus under unloaded and upright-loaded conditions in patients with early knee OA.
Twelve patients with early knee OA and 18 healthy adult volunteers participated in this study. Magnetic resonance imaging using special equipment was performed with the participants in the unloaded and upright-loaded conditions. Medial, anterior, and posterior extrusions of the medial meniscus against the tibial edge were evaluated and compared between the early knee OA and healthy adult control groups. Additionally, 12 patients in the early knee OA group were divided into 2 subgroups based on whether MMPRT was observed, and the extrusion of the medial meniscus was compared.
The amount of medial extrusion of the medial meniscus in both the unloaded and upright-loaded conditions was significantly greater in the early knee OA group than in the control group (unloaded: 2.6 ± 1.0 mm vs 0.7 ± 0.5 mm; upright-loaded: 3.7 ± 0.9 mm vs 1.8 ± 0.8 mm). Similarly, the anterior and posterior extrusion of the medial meniscus in the upright-loaded condition was significantly larger in the early knee OA group (anterior: 4.6 ± 1.0 mm vs 3.7 ± 1.1 mm; posterior: -3.4 ± 1.1 mm vs -4.6 ± 1.6 mm). However, no difference was observed in meniscal extrusion between unloaded and upright-loaded conditions. The posterior extrusion of the medial meniscus in the upright-loaded condition was significantly greater in MMPRT cases than in non-MMPRT cases in the early knee OA group (MMPRT: -2.7 ± 1.1 mm; non-MMPRT -4.1 ± 1.5 mm).
In early knee OA, significantly large meniscal extrusions of the medial meniscus in both unloaded and upright-loaded conditions were found compared with healthy adults. Among patients with early knee OA, those with MMPRT showed a large posterior extrusion of the medial meniscus in the upright-loaded condition compared with those without MMPRT.
Level IV.
内侧半月板形态和运动在早期膝骨关节炎（OA）或内侧半月板后根撕裂（MMPRT）下是否在直立负重条件下发生尚不清楚。本研究旨在评估早期膝 OA 患者在无负荷和直立负荷条件下内侧半月板的内外侧挤压。
12 例早期膝 OA 患者和 18 例健康成年志愿者参加了本研究。使用特殊设备进行磁共振成像，分别在无负荷和直立负荷条件下对参与者进行检查。评估并比较了内侧半月板在胫骨边缘的内侧、前侧和后侧的挤出量，比较了早期膝 OA 组和健康成人对照组。此外，根据是否观察到 MMPRT，将早期膝 OA 组的 12 例患者分为 2 个亚组，并比较了内侧半月板的挤出量。
在无负荷和直立负荷条件下，早期膝 OA 组内侧半月板的内侧挤出量均明显大于对照组（无负荷：2.6±1.0mm 比 0.7±0.5mm；直立负荷：3.7±0.9mm 比 1.8±0.8mm）。同样，在直立负荷条件下，内侧半月板的前侧和后侧挤出量在早期膝 OA 组也明显较大（前侧：4.6±1.0mm 比 3.7±1.1mm；后侧：-3.4±1.1mm 比-4.6±1.6mm）。然而，在无负荷和直立负荷条件下，半月板挤出量无差异。在早期膝 OA 组中，与非 MMPRT 病例相比，MMPRT 病例的内侧半月板在直立负荷条件下的后外侧挤出量明显更大（MMPRT：-2.7±1.1mm；非 MMPRT：-4.1±1.5mm）。
在早期膝 OA 中，与健康成年人相比，无负荷和直立负荷条件下内侧半月板的明显大挤出量。在早期膝 OA 患者中，与非 MMPRT 病例相比，MMPRT 病例在直立负荷条件下的内侧半月板后外侧挤出量较大。
IV 级。
