Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Iran J Kidney Dis. 2023 Jul;17(4):184-190.
Early diagnosis and management of preeclampsia are very important to reduce fetal and maternal complications. In this study, we examined the ratio of protein to creatinine in a random urine sample and its relationship to the rate of 24-hour urine protein excretion for quick detection and prompt management of this condition in women with preeclampsia.
In this descriptive-analytical cross-sectional study, 60 pregnant women with preeclampsia referred to the maternity ward of Ali Ebn -e Abitaleb hospital of Zahedan in 2019 were recruited. The 24-hour urine protein excretion and the ratio of protein to creatinine in a random urine sample were compared in these patients.
The results showed that there was a positive correlation between the 24-hour urinary protein excretion and the protein to creatinine ratio of the random urine sample in preeclampsia (P < .001, r = 0.515). Women with a higher 24-hour protein excretion also had a higher urinary protein to creatinine ratio.
In general, based on the results of this study, it can be concluded that the ratio of protein to creatinine in the random urine sample has a good diagnostic efficiency in suspected preeclampsia. It is a quick alternative method for detecting suspicious proteinuria and could be used as a screening test in emergency situations. DOI: 10.52547/ijkd.7457.
及早诊断和处理子痫前期对降低母婴并发症非常重要。本研究通过检测随机尿样中蛋白与肌酐的比值，探讨其与 24 小时尿蛋白排泄率的关系，以期快速发现子痫前期患者并及时进行处理。
本研究为描述性分析性横断面研究，纳入了 2019 年在扎黑丹阿里·伊本·阿比塔勒卜医院妇产科就诊的 60 例子痫前期孕妇。比较了这些患者的 24 小时尿蛋白排泄量和随机尿样中蛋白与肌酐的比值。
结果表明，子痫前期患者的 24 小时尿蛋白排泄量与随机尿样中蛋白与肌酐的比值呈正相关（P<0.001，r=0.515）。24 小时尿蛋白排泄量较高的患者，其随机尿样中蛋白与肌酐的比值也较高。
总体而言，根据本研究结果，可以得出结论，随机尿样中蛋白与肌酐的比值对子痫前期的诊断具有较好的效率。它是一种快速替代方法，用于检测可疑蛋白尿，可作为紧急情况下的筛选试验。DOI: 10.52547/ijkd.7457.
