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多发性骨瘤的经典及罕见表现:一例报告

Classic and rare manifestations of multiple osteoma: A case report.

作者信息

Putro Yuni Artha Prabowo, Magetsari Rahadyan, Taroeno-Hariadi Kartika W, Dwianingsih Ery Kus, Pribadi Amri Wicaksono, Sukotjo Karisa Kartika

机构信息

Department of Orthopedics and Traumatology, RSUP Dr. Sardjito Hospital, Jl. Kesehatan Sendowo No.1, Sleman 55281, D.I.Yogyakarta, Indonesia; Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jl. Farmako, Sendowo, Sekip Utara, Sleman 55281, D.I.Yogyakarta, Indonesia.

Department of Orthopedics and Traumatology, RSUP Dr. Sardjito Hospital, Jl. Kesehatan Sendowo No.1, Sleman 55281, D.I.Yogyakarta, Indonesia; Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jl. Farmako, Sendowo, Sekip Utara, Sleman 55281, D.I.Yogyakarta, Indonesia.

出版信息

Int J Surg Case Rep. 2023 Sep;110:108713. doi: 10.1016/j.ijscr.2023.108713. Epub 2023 Aug 25.

Abstract

INTRODUCTION AND IMPORTANCE

Osteoma is a benign tumor that can arise from compact or cancellous bone and is more commonly found in the face or skull. The incidence of osteoma believed to be underreported as most are asymptomatic. To date, the best modality to diagnose osteoma is CT scan. We report a unique case of osteoma presenting with cranial and extracranial manifestations and highlight the importance of bone survey in evaluating patients with osteoma.

CASE PRESENTATION

A 26-year-old female complained of bilateral pain in the jawbone and several areas of her head. On physical examination, there were several masses in the head with the largest on the left mandible measuring 5.6 × 6.0 × 4.5 cm from MSCT examination. Hemi-mandibulectomy, histopathological and cytopathology examination were performed on the tissue obtained from the left mandible which concluded osteoma. Post-operative bone survey was performed and found osteoma on left ulna and bilateral fibula. Suspected Gardner syndrome with multiple osteoma manifestation was excluded from normal results of colon in-loop examination. We conservatively monitored the patient and most recent 6-month follow-up found no complaint nor changes in the extracranial osteoma manifestation on left ulna and both fibulas.

CLINICAL DISCUSSION

The benign tumor osteoma is incredibly uncommon to present both intra and extracranially. We suggest thorough skeletal studies such as bone survey to be performed as they are crucial in the full evaluation of patients with multiple osteomas. Osteoma treatment is based on the patient's symptoms, surgery for patients with symptoms and periodic monitoring for asymptomatic patients.

CONCLUSION

It is necessary to consider radiological modality for diagnosing osteoma patients. The majority of osteomas are asymptomatic and the choice of radiological examination sometimes still misses the lesion. It is important to evaluate histologically if the lesion difficult to diagnose.

摘要

引言与重要性

骨瘤是一种可起源于密质骨或松质骨的良性肿瘤,更常见于面部或颅骨。骨瘤的发病率据信被低估了,因为大多数骨瘤是无症状的。迄今为止,诊断骨瘤的最佳方式是CT扫描。我们报告了一例表现为颅内和颅外症状的独特骨瘤病例,并强调了骨骼检查在评估骨瘤患者中的重要性。

病例介绍

一名26岁女性主诉颌骨及头部多个部位双侧疼痛。体格检查发现头部有多个肿块,其中最大的位于左下颌骨,多层螺旋CT检查显示其大小为5.6×6.0×4.5厘米。对取自左下颌骨的组织进行了半侧下颌骨切除术、组织病理学和细胞病理学检查,结果诊断为骨瘤。术后进行了骨骼检查,发现左尺骨和双侧腓骨有骨瘤。结肠袢检查结果正常,排除了疑似伴有多种骨瘤表现的加德纳综合征。我们对患者进行了保守监测,最近6个月的随访发现,患者没有不适主诉,左尺骨和双侧腓骨的颅外骨瘤表现也没有变化。

临床讨论

良性肿瘤骨瘤同时出现颅内和颅外症状极为罕见。我们建议进行全面的骨骼检查,如骨骼检查,因为它们对于全面评估多发性骨瘤患者至关重要。骨瘤的治疗基于患者的症状,有症状的患者进行手术,无症状的患者进行定期监测。

结论

对于骨瘤患者,有必要考虑采用放射学检查方式。大多数骨瘤是无症状的,放射学检查的选择有时仍会漏诊病变。对于难以诊断的病变,进行组织学评估很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f61/10509817/248d0f68f014/gr1.jpg

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