尸体模型中拇内收肌痉挛的肌内神经分布与肉毒毒素治疗的关系。
Intramuscular Neural Distribution of Adductor Pollicis Muscle Spasticity in Cadaver Model Regarding Botulinum Neurotoxin Treatment.
机构信息
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.
Maylin Clinic (Apgujeong), Seoul, Korea.
出版信息
Yonsei Med J. 2023 Sep;64(9):581-585. doi: 10.3349/ymj.2023.0111.
PURPOSE
The adductor pollicis muscle is frequently targeted for botulinum neurotoxin injective treatment for spasticity. However, there are no injective guidelines for delivering injection to the muscle.
MATERIALS AND METHODS
A method known as the modified Sihler's method was used to stain the adductor pollicis muscle in 16 specimens to reveal intramuscular neural distribution of the muscle.
RESULTS
The most intramuscular neural distribution was located on 1/5 to 3/5 of the muscle regarding midline of 3rd metacarpal bone (0) to the base of the 1st proximal phalanx (5/5). The nerve entry point was mostly located on 0 to 1/5 of the muscle.
CONCLUSION
The result suggests that botulinum neurotoxin should be delivered at the middle of second metacarpal bone via deep injection.
目的
内收拇指肌常被作为痉挛性疾病的肉毒毒素注射治疗靶点。然而，目前尚缺乏针对该肌肉的注射治疗指南。
材料与方法
采用改良 Sihler's 法对 16 个标本的内收拇指肌进行染色，以显示肌肉内的神经分布。
结果
关于第 3 掌骨中线（0）到第 1 近节指骨基部（5/5），内收拇指肌的神经分布最密集的部位位于 1/5 到 3/5 处。神经进入点多位于 0 到 1/5 处。
结论
研究结果提示肉毒毒素应通过深部注射至第 2 掌骨中段进行给药。
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