Bulpitt C J, Bulpitt P F, Daymond M, Hartley K, Dollery C T
Postgrad Med J. 1986 May;62(727):335-40. doi: 10.1136/pgmj.62.727.335.
The survival has been determined for the 404 patients who presented to the Hammersmith Hospital Hypertension Clinic during the years 1962 to 1966 and in whom the untreated blood pressure was known. The fifteen year survival ranged from 72% for young men aged 30-49 at presentation to 27% for men aged 60-69. Sixty-eight percent of the deaths were cardiovascular or renal, 33% of all deaths were from ischaemic heart disease (IHD), 17% from stroke and 3% from renal causes. Death from any cause was predicted with statistical significance by age, the presence of accelerated or malignant hypertension, impaired renal function, smoking at presentation and systolic blood pressure. Death was not predicted by hypokalaemia, hyperuricaemia (after adjusting for renal function) and obesity.
已确定了1962年至1966年间前往哈默史密斯医院高血压诊所就诊且已知未经治疗血压情况的404名患者的生存率。15年生存率从就诊时年龄在30 - 49岁的年轻男性的72%到60 - 69岁男性的27%不等。68%的死亡是心血管或肾脏原因导致的,所有死亡中有33%死于缺血性心脏病(IHD),17%死于中风,3%死于肾脏疾病。年龄、存在急进性或恶性高血压、肾功能受损、就诊时吸烟和收缩压对任何原因导致的死亡都具有统计学意义的预测作用。低钾血症、高尿酸血症(在调整肾功能后)和肥胖对死亡没有预测作用。