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在一家医院诊所就诊的高血压患者的15年生存率。

Fifteen year survival of patients presenting with hypertension to a hospital clinic.

作者信息

Bulpitt C J, Bulpitt P F, Daymond M, Hartley K, Dollery C T

出版信息

Postgrad Med J. 1986 May;62(727):335-40. doi: 10.1136/pgmj.62.727.335.

DOI:10.1136/pgmj.62.727.335
PMID:3763539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2418698/
Abstract

The survival has been determined for the 404 patients who presented to the Hammersmith Hospital Hypertension Clinic during the years 1962 to 1966 and in whom the untreated blood pressure was known. The fifteen year survival ranged from 72% for young men aged 30-49 at presentation to 27% for men aged 60-69. Sixty-eight percent of the deaths were cardiovascular or renal, 33% of all deaths were from ischaemic heart disease (IHD), 17% from stroke and 3% from renal causes. Death from any cause was predicted with statistical significance by age, the presence of accelerated or malignant hypertension, impaired renal function, smoking at presentation and systolic blood pressure. Death was not predicted by hypokalaemia, hyperuricaemia (after adjusting for renal function) and obesity.

摘要

已确定了1962年至1966年间前往哈默史密斯医院高血压诊所就诊且已知未经治疗血压情况的404名患者的生存率。15年生存率从就诊时年龄在30 - 49岁的年轻男性的72%到60 - 69岁男性的27%不等。68%的死亡是心血管或肾脏原因导致的,所有死亡中有33%死于缺血性心脏病(IHD),17%死于中风,3%死于肾脏疾病。年龄、存在急进性或恶性高血压、肾功能受损、就诊时吸烟和收缩压对任何原因导致的死亡都具有统计学意义的预测作用。低钾血症、高尿酸血症(在调整肾功能后)和肥胖对死亡没有预测作用。

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本文引用的文献

1
Calculation of survival rates for cancer.癌症生存率的计算
Proc Staff Meet Mayo Clin. 1950 May 24;25(11):270-86.
2
Prognosis of treated hypertension. Changes in life expectancy and causes of death between 1952 and 1967.高血压治疗的预后。1952年至1967年间预期寿命的变化及死亡原因。
Q J Med. 1970 Jul;39(155):411-29.
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A computer program for comparing K samples with right-censored data.一个用于比较有删失数据的K个样本的计算机程序。
Comput Programs Biomed. 1972 Nov;2(4):315-21. doi: 10.1016/0010-468x(72)90019-0.
4
Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial.欧洲老年高血压工作组试验的死亡率和发病率结果。
Lancet. 1985 Jun 15;1(8442):1349-54. doi: 10.1016/s0140-6736(85)91783-0.
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Risk factors for death in treated hypertensive patients. Report from the D.H.S.S. Hypertension Care Computing Project.接受治疗的高血压患者的死亡风险因素。来自卫生和社会保障部高血压护理计算机项目的报告。
Lancet. 1979 Jul 21;2(8134):134-7. doi: 10.1016/s0140-6736(79)90013-8.