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创伤外科中骨移植的当前概念。

Current concepts of bone grafting in trauma surgery.

作者信息

Nashi Nazrul, Kagda Fareed Hy

机构信息

University Orthopaedic, Hand and Reconstructive Microsurgery Cluster, National University Health System, Singapore, 1E Kent Ridge Road, 119228, Singapore.

Department of Orthopaedic Surgery, Ng Teng Fong General Hospital, National University Health System, Singapore, 1 Jurong East Street 21, 609606, Singapore.

出版信息

J Clin Orthop Trauma. 2023 Aug 5;43:102231. doi: 10.1016/j.jcot.2023.102231. eCollection 2023 Aug.


DOI:10.1016/j.jcot.2023.102231
PMID:37636005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10448478/
Abstract

Bone graft in trauma surgery is commonly used in managing bone defects, non-union, fracture related infections, arthrodesis or to provide structural support in fractures. A variety of bone grafts are made available to the treating physician, which includes autograft, allograft and bone graft substitutes. The future of bone grafting in trauma surgery is exciting with the incorporation of technological advancement such as gene therapy, 3D-printing and tissue engineering. Regardless, there are still limitations to what we understand regarding current bone grafting techniques with conflicting literature on their clinical utility and indication. The aim of this review article therefore is to take a step back and critically evaluate the current concepts of bone grafting in trauma surgery, with special emphasis made on reviewing the types of bone graft, biology of bone graft incorporation and indication for its use in various clinical scenarios.

摘要

骨移植在创伤外科手术中常用于处理骨缺损、骨不连、骨折相关感染、关节融合或为骨折提供结构支撑。治疗医生可使用多种骨移植材料,包括自体骨移植、异体骨移植和骨移植替代物。随着基因治疗、3D打印和组织工程等技术进步的融入,创伤外科手术中骨移植的未来令人期待。尽管如此,我们对当前骨移植技术的理解仍存在局限性,关于其临床效用和适应症的文献相互矛盾。因此,这篇综述文章的目的是退一步,批判性地评估创伤外科手术中骨移植的当前概念,特别强调回顾骨移植的类型、骨移植融合的生物学机制及其在各种临床场景中的使用适应症。

相似文献

[1]
Current concepts of bone grafting in trauma surgery.

J Clin Orthop Trauma. 2023-8-5

[2]
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[3]
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[4]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
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Int J Mol Sci. 2025-6-4

[2]
Allografts promote skeletal regeneration of periprosthetic femoral bone loss.

J Orthop Translat. 2025-4-23

[3]
The impact of autogenous bone grafts on the regeneration of radial bone defects in rabbits compared to autogenous advanced platelet-rich fibrin plus.

Open Vet J. 2025-1

[4]
Locally Delivered Antibiotics in Fracture-Related Infection.

Cureus. 2024-11-7

[5]
In Vivo Evaluation of Demineralized Bone Matrix with Cancellous Bone Putty Formed Using Hydroxyethyl Cellulose as an Allograft Material in a Canine Tibial Defect Model.

Animals (Basel). 2024-10-17

本文引用的文献

[1]
Joint depression in tibial plateau fractures: To bone graft or not to bone graft?

Injury. 2023-3-2

[2]
Effect of Fibular Allograft Augmentation in Medial Column Comminuted Proximal Humeral Fractures: A Randomized Controlled Trial.

J Bone Joint Surg Am. 2023-2-15

[3]
Fixation of Fresh Femoral Neck Fractures Using Fibular Strut Graft Along with Cannulated Screws.

Ortop Traumatol Rehabil. 2022-10-31

[4]
Treatment of tibial bone defects: pilot analysis of direct medical costs between distraction osteogenesis with an Ilizarov frame and the Masquelet technique.

Eur J Trauma Emerg Surg. 2023-4

[5]
Bone grafting for scaphoid nonunion surgery : a systematic review and meta-analysis.

Bone Joint J. 2022-5

[6]
Osteochondral autograft transplantation in the treatment of AO/OTA type C3 tibial plafond fractures with irreducibly comminuted area and/or cartilage delamination in the distal tibial facet.

Injury. 2022-4

[7]
Improved outcomes for proximal humerus fracture open reduction internal fixation augmented with a fibular allograft in elderly patients: a systematic review and meta-analysis.

J Shoulder Elbow Surg. 2022-4

[8]
Union Rates of Talar Neck Fractures With Substantial Bone Defects Treated With Autograft.

Foot Ankle Int. 2022-3

[9]
Biomechanical study of Proximal humeral fracture fixation: Locking plate with medial support screw vs. locking plate with intramedullary fibular graft.

Clin Biomech (Bristol). 2021-12

[10]
Bone Grafts in Trauma and Orthopaedics.

Cureus. 2021-9-4

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