Sarraf Deependra Prasad, Gupta Pramendra Prasad
Department of Clinical Pharmacology and Therapeutics, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Department of General Practice and Emergency Medicine, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
J Family Med Prim Care. 2023 Jun;12(6):1190-1196. doi: 10.4103/jfmpc.jfmpc_90_23. Epub 2023 Jun 30.
Poor glycemic control in type 2 diabetes mellitus (T2DM) causes damage to various organs and leads to the development of disabling and life-threatening complications.
To find out the prevalence of glycemic control and medication adherence (MA) and the factors affecting them.
A cross-sectional study was conducted among patients with T2DM. The patients were categorized as good glycemic control (HbA <7.0%) and poor glycemic control (HbA ≥7.0%). MA was categorized as low (score <6), medium (score 6 or 7), and high (score 8). The Statistical Package for Social Science (version 11.5) was used for statistical analysis at a value less than 0.05.
Of 129 patients, 65 (50.39%) were females. The mean age was 48.33 ± 12.86 years. The combination of metformin and glimepiride was prescribed to 37 (28.68%) patients. Diabetic knowledge was poor in 84 (65.12%) patients. Glycemic control was good in 108 (83.72%) patients. MA was medium in 72 (55.81%) patients. Patients taking regular fruit, having shorter duration of drug therapy, and having good diabetic knowledge had good glycemic control and were statistically significant ( value < 0.05). Patients having family support, nonalcoholic, taking regular fruit, being involved in daily jogging, having shorter duration of drug therapy, and having good diabetic knowledge had high MA and were statistically significant ( value < 0.05).
The majority of the diabetic patients had good glycemic control and medium MA. Patients taking regular fruit, being involved in daily jogging, having a shorter duration of drug therapy, and having good diabetic knowledge were identified as factors that affect both glycemic control and MA.
2型糖尿病（T2DM）患者血糖控制不佳会损害多个器官，并导致致残和危及生命的并发症。
了解血糖控制和药物依从性（MA）的患病率及其影响因素。
对T2DM患者进行横断面研究。患者被分为血糖控制良好（糖化血红蛋白<7.0%）和血糖控制不佳（糖化血红蛋白≥7.0%）。MA分为低（得分<6）、中（得分6或7）和高（得分8）。使用社会科学统计软件包（版本11.5）进行统计分析，P值小于0.05。
129例患者中，65例（50.39%）为女性。平均年龄为48.33±12.86岁。37例（28.68%）患者使用二甲双胍和格列美脲联合治疗。84例（65.12%）患者糖尿病知识较差。108例（83.72%）患者血糖控制良好。72例（55.81%）患者MA为中等。经常吃水果、药物治疗时间较短且糖尿病知识良好的患者血糖控制良好，差异有统计学意义（P值<0.05）。有家庭支持、不饮酒、经常吃水果、每天慢跑、药物治疗时间较短且糖尿病知识良好的患者MA较高，差异有统计学意义（P值<0.05）。
大多数糖尿病患者血糖控制良好且MA为中等。经常吃水果、每天慢跑、药物治疗时间较短且糖尿病知识良好被确定为影响血糖控制和MA的因素。
