Wise D A, Eldred N L
Pharmacol Biochem Behav. 1986 Aug;25(2):449-56. doi: 10.1016/0091-3057(86)90022-5.
Adding maternal social stress, induced by housing in pairs, to maternal consumption of high-calorie fluids adversely affected hamster reproduction. Pregnancy outcomes of 67 dams housed either alone or in pairs, and given either water (WAT), or isocaloric solutions of either 30% ethanol (ETH), sucrose (SUC) or propylene glycol (PG), were compared. Pups of unpaired dams drinking any high-calorie fluid weighed less than those drinking water, but no other deficits were found. Among paired dams, those designated submissive on the basis of agonistic behavior and drinking either SUC, ETH, or PG, had fewer viable pups and more fetal resorptions and stillborn pups than WAT dams. Also, dominant PG dams delivered few pups and both dominant and submissive PG dams delivered malformed pups or embryos. Whether paired or unpaired, litters of SUC and ETH dams were similar. Drinking any high-calorie fluid reduced maternal food and fluid intake and weight gains below that of water, but pairing had no additional effect on dams.
将成对饲养所引发的母体社会压力与母体高热量液体的摄入相结合,会对仓鼠繁殖产生不利影响。比较了67只单独饲养或成对饲养的母鼠的妊娠结局,这些母鼠分别给予水(WAT)、30%乙醇等热量溶液(ETH)、蔗糖(SUC)或丙二醇(PG)。饮用任何高热量液体的未配对母鼠所产幼崽的体重均低于饮用纯水的母鼠,但未发现其他缺陷。在成对饲养的母鼠中,根据争斗行为被认定为顺从且饮用SUC、ETH或PG的母鼠,与饮用WAT的母鼠相比,存活幼崽数量更少,胎儿吸收和死产幼崽更多。此外,占主导地位的PG母鼠产仔很少,而占主导地位和顺从的PG母鼠都会产出畸形幼崽或胚胎。无论是否成对饲养,SUC和ETH母鼠的窝仔情况相似。饮用任何高热量液体都会使母体的食物和液体摄入量以及体重增加低于饮用纯水的情况,但成对饲养对母鼠没有额外影响。