鼻中隔成形术后抗生素和夹板对鼻中隔黏膜培养结果影响的评估
Evaluation of the Effect of Antibiotics and Splints on the Result of Septal Mucosal Culture After Septoplasty.
作者信息
Sedaghat Kianoosh, Hosseinpoor Masoumeh, Nasirai Ehsan, Yousefi Razieh, Akbari Shadi, Rasoulian Bashir
机构信息
Otorhinolaryngology department, Mashhad University of Medical Sciences, Otorhinolaryngologist, Mashhad, MD Iran.
Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
出版信息
Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):1586-1590. doi: 10.1007/s12070-023-03665-w. Epub 2023 Mar 22.
PURPOSE
Post operation infection after septoplasty is very rare, possibly due to excessive nasal blood supply. Most otorhinolaryngologists recommend antibiotics after septoplasty; however, controversial results were available. Therefore, this study was designed to investigate the effect of antibiotics after septoplasty.
METHODS
In this study, 90 patients who were candidates for septoplasty were entered the study and divided into three groups. The first group did not receive any oral antibiotics after septoplasty. The second group took 500 mg of oral cephalexin. The third group, for whom splints were used, also received cephalexin. The culture of the nasal mucosa was prepared before and two weeks after surgery and compared between groups. Then, the amount and types of mucosa microorganisms were reported. Data were analyzed using SPSS16.
RESULTS
The growth significantly increased in the first group (p = 0.051) and reduced in the second group (p < 0.001). While a decreased growth rate was observed in the third group, it was not statistically significant (p = 0.12).
CONCLUSION
The present study highlighted the beneficial role of prophylactic antibiotics administration in patients without splints on bacterial growth, while it had no effect in patients with splints.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s12070-023-03665-w.
目的
鼻中隔成形术后的手术感染非常罕见，可能是由于鼻腔血液供应过多。大多数耳鼻喉科医生建议在鼻中隔成形术后使用抗生素；然而，结果存在争议。因此，本研究旨在调查鼻中隔成形术后使用抗生素的效果。
方法
在本研究中，90例鼻中隔成形术候选患者进入研究并分为三组。第一组在鼻中隔成形术后未接受任何口服抗生素。第二组服用500毫克口服头孢氨苄。第三组使用了夹板，也接受了头孢氨苄。在手术前和术后两周制备鼻黏膜培养物，并在组间进行比较。然后，报告黏膜微生物的数量和类型。使用SPSS16分析数据。
结果
第一组的生长显著增加（p = 0.051），第二组减少（p < 0.001）。虽然第三组观察到生长速率下降，但无统计学意义（p = 0.12）。
结论
本研究强调了预防性使用抗生素对无夹板患者细菌生长的有益作用，而对有夹板患者则无效果。
补充信息
在线版本包含可在10.1007/s12070-023-03665-w获取的补充材料。
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