Nakajima Hiroyuki, Tokunaga Chiho, Yoshitake Akihiro, Takazawa Akitoshi
Department of Cardiovascular Surgery, International Medical Center, Saitama Medical University, 1397-1, Yamane, Hidaka, Saitama 350-1298, Japan.
Eur Heart J Case Rep. 2023 Aug 17;7(8):ytad392. doi: 10.1093/ehjcr/ytad392. eCollection 2023 Aug.
Mechanisms of paravalvular leak (PVL) after mitral valve replacement have not been fully delineated. Herein, we report a case of structures on the ventricular side of the mitral valve in a patient with an extremely late PVL.
A 68-year-old female underwent aortic and mitral valve replacement with a mechanical valve 29 years ago. She was in good health for 28 years. However, exertional dyspnoea appeared 8 months ago. She was admitted to our hospital for congestive heart failure and haemolytic anaemia. Echocardiography showed severe regurgitation due to PVL of the mitral valve. The fluoroscopy showed that a circular calcification was found below the mitral prosthesis. The operation was performed through a median sternotomy. After the aortic cross-clamp, the aortic mechanical valve was removed. The ventricular side of the mitral valve was inspected with the endoscope through the aortic annulus before manoeuvers were performed in the mitral valve. A gap was seen between the prosthetic valve and annular tissue and subvalvular calcification. A bioprosthetic valve was placed with a modified collar-reinforcement technique using a xenopericardium strip. The postoperative course was uneventful. PVL and haemolysis completely disappeared.
The ventricular side of the prosthetic valve could be observed before the mitral valve was removed. Not only the protruding circular calcification and displacement of the prosthetic valve to the atrial side but also the loss of adhesion and adhesive nature of the annular tissue played a definitive role in the late PVL occurrence and recurrence after percutaneous or surgical repair.
二尖瓣置换术后瓣周漏(PVL)的机制尚未完全阐明。在此,我们报告一例二尖瓣心室侧结构导致极晚期PVL的病例。
一名68岁女性29年前接受了主动脉瓣和二尖瓣置换术,植入了机械瓣膜。她健康状况良好达28年。然而,8个月前出现劳力性呼吸困难。她因充血性心力衰竭和溶血性贫血入院。超声心动图显示二尖瓣PVL导致严重反流。荧光透视显示二尖瓣人工瓣膜下方有圆形钙化。通过正中胸骨切开术进行手术。在阻断主动脉后,移除主动脉机械瓣膜。在对二尖瓣进行操作前,通过主动脉瓣环用内窥镜检查二尖瓣的心室侧。可见人工瓣膜与瓣环组织之间有间隙以及瓣下钙化。采用异种心包条带,运用改良的环加强技术植入生物人工瓣膜。术后病程顺利。PVL和溶血完全消失。
在移除二尖瓣之前可以观察到人工瓣膜的心室侧。不仅人工瓣膜突出的圆形钙化以及向心房侧的移位,而且瓣环组织粘连和粘着性的丧失在经皮或手术修复后晚期PVL的发生和复发中起了决定性作用。