• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Editorial: Lipid droplets and mitochondria in metabolic diseases.

作者信息

Su Wen, Chi Yujing, An Yu A

机构信息

Department of Pathophysiology, Shenzhen University Health Science Center, Shenzhen University, Shenzhen, China.

Department of Central Laboratory and Institute of Clinical Molecular Biology, Peking University People's Hospital, Beijing, China.

出版信息

Front Physiol. 2023 Aug 11;14:1266356. doi: 10.3389/fphys.2023.1266356. eCollection 2023.

DOI:10.3389/fphys.2023.1266356
PMID:37637148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10455923/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa0d/10455923/a592440f6b61/fphys-14-1266356-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa0d/10455923/a592440f6b61/fphys-14-1266356-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa0d/10455923/a592440f6b61/fphys-14-1266356-g001.jpg

相似文献

1
Editorial: Lipid droplets and mitochondria in metabolic diseases.社论:代谢性疾病中的脂滴与线粒体
Front Physiol. 2023 Aug 11;14:1266356. doi: 10.3389/fphys.2023.1266356. eCollection 2023.
2
Lipid-droplet associated mitochondria promote fatty-acid oxidation through a distinct bioenergetic pattern in male Wistar rats.脂滴相关的线粒体通过雄性 Wistar 大鼠独特的生物能量模式促进脂肪酸氧化。
Nat Commun. 2023 Feb 11;14(1):766. doi: 10.1038/s41467-023-36432-0.
3
Lipophagy: A potential therapeutic target for nonalcoholic and alcoholic fatty liver disease.脂噬作用:非酒精性和酒精性脂肪肝疾病的潜在治疗靶点。
Biochem Biophys Res Commun. 2023 Sep 10;672:36-44. doi: 10.1016/j.bbrc.2023.06.030. Epub 2023 Jun 14.
4
Widespread expression of perilipin 5 in normal human tissues and in diseases is restricted to distinct lipid droplet subpopulations. perilipin 5 在正常人体组织和疾病中的广泛表达仅限于特定的脂滴亚群。
Cell Tissue Res. 2018 Oct;374(1):121-136. doi: 10.1007/s00441-018-2845-7. Epub 2018 May 11.
5
Adipose differentiation-related protein is a reliable lipid droplet marker in alcoholic fatty liver of rats.脂肪分化相关蛋白是大鼠酒精性脂肪肝中一种可靠的脂滴标志物。
Alcohol Clin Exp Res. 2008 Apr;32(4):683-9. doi: 10.1111/j.1530-0277.2008.00624.x. Epub 2008 Mar 13.
6
BNIP3 in hypoxia-induced mitophagy: Novel insights and promising target for non-alcoholic fatty liver disease.BNIP3 在低氧诱导的线粒体自噬中的作用:非酒精性脂肪性肝病的新见解和有前景的靶点。
Int J Biochem Cell Biol. 2024 Mar;168:106517. doi: 10.1016/j.biocel.2024.106517. Epub 2024 Jan 11.
7
Lipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damage.酒精性肝病中与脂滴相关的蛋白质:与肝细胞损伤的潜在联系。
Int J Clin Exp Pathol. 2015 Aug 1;8(8):8699-708. eCollection 2015.
8
Lipid droplets promote efficient mitophagy.脂滴促进有效的线粒体自噬。
Autophagy. 2023 Feb;19(2):724-725. doi: 10.1080/15548627.2022.2089956. Epub 2022 Aug 8.
9
Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes.缺氧诱导的脂滴相关蛋白诱导 DGAT1 并促进肝细胞中的脂质储存。
Mol Metab. 2021 May;47:101168. doi: 10.1016/j.molmet.2021.101168. Epub 2021 Jan 16.
10
Hepatic stellate cells and liver retinoid content in alcoholic liver disease in humans.人类酒精性肝病中的肝星状细胞与肝脏类视黄醇含量
Alcohol Clin Exp Res. 1998 Apr;22(2):494-500.

引用本文的文献

1
Adipocyte metabolic state regulates glial phagocytic function.脂肪细胞代谢状态调节神经胶质细胞吞噬功能。
Cell Rep. 2025 May 27;44(5):115704. doi: 10.1016/j.celrep.2025.115704. Epub 2025 May 14.
2
Integrative Transcriptomics and Proteomics Analysis Reveals 's Role in Lipid Metabolism.整合转录组学和蛋白质组学分析揭示了……在脂质代谢中的作用。 (原文中's指代不明,翻译时保留原文格式)
Genes (Basel). 2024 Nov 30;15(12):1562. doi: 10.3390/genes15121562.
3
Regulation of Mitochondrial and Peroxisomal Metabolism in Female Obesity and Type 2 Diabetes.女性肥胖和 2 型糖尿病中线粒体和过氧化物酶体代谢的调节。

本文引用的文献

1
Aflatoxin B1 exposure triggers hepatic lipotoxicity via p53 and perilipin 2 interaction-mediated mitochondria-lipid droplet contacts: An in vitro and in vivo assessment.黄曲霉毒素 B1 暴露通过 p53 和 perilipin 2 相互作用介导的线粒体-脂滴接触引发肝脂肪毒性:一项体外和体内评估。
J Hazard Mater. 2023 Mar 5;445:130584. doi: 10.1016/j.jhazmat.2022.130584. Epub 2022 Dec 13.
2
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.Rab8a 作为骨骼肌中脂滴的线粒体受体。
Dev Cell. 2023 Feb 27;58(4):289-305.e6. doi: 10.1016/j.devcel.2023.01.007. Epub 2023 Feb 16.
3
Creb-Pgc1α pathway modulates the interaction between lipid droplets and mitochondria and influences high fat diet-induced changes of lipid metabolism in the liver and isolated hepatocytes of yellow catfish.
Int J Mol Sci. 2024 Oct 19;25(20):11237. doi: 10.3390/ijms252011237.
4
Adipocyte metabolic state regulates glial phagocytic function.脂肪细胞代谢状态调节神经胶质细胞吞噬功能。
bioRxiv. 2024 Sep 24:2024.09.24.614765. doi: 10.1101/2024.09.24.614765.
5
dldhcri3 zebrafish exhibit altered mitochondrial ultrastructure, morphology, and dysfunction partially rescued by probucol or thiamine.dl dhcri3 斑马鱼表现出线粒体超微结构、形态改变和功能障碍,可部分通过普罗布考或硫胺素挽救。
JCI Insight. 2024 Aug 20;9(18):e178973. doi: 10.1172/jci.insight.178973.
6
Lipid Droplet-Mitochondria Contacts in Health and Disease.脂滴-线粒体接触在健康和疾病中的作用。
Int J Mol Sci. 2024 Jun 22;25(13):6878. doi: 10.3390/ijms25136878.
Creb-Pgc1α 通路调节脂滴与线粒体的相互作用,并影响高脂饮食诱导的黄颡鱼肝和原代肝细胞中脂质代谢的变化。
J Nutr Biochem. 2020 Jun;80:108364. doi: 10.1016/j.jnutbio.2020.108364. Epub 2020 Feb 28.
4
MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes.MIGA2 将线粒体、内质网和脂滴联系起来,并促进脂肪细胞中的从头脂肪生成。
Mol Cell. 2019 Dec 5;76(5):811-825.e14. doi: 10.1016/j.molcel.2019.09.011. Epub 2019 Oct 15.
5
Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells.脂肪酶关联蛋白 5 通过增强 HepG2 细胞线粒体功能来防止细胞氧化应激。
Cells. 2019 Oct 11;8(10):1241. doi: 10.3390/cells8101241.
6
Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.长链酰基辅酶 A 合成酶 1 与激活和定向脂肪酸进入特定肝途径的关键蛋白相互作用。
J Biol Chem. 2018 Oct 26;293(43):16724-16740. doi: 10.1074/jbc.RA118.004049. Epub 2018 Sep 6.
7
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria.内质网酶二酰甘油酰基转移酶2(DGAT2)存在于线粒体相关膜中,并且具有促进其与线粒体结合的线粒体靶向信号。
J Biol Chem. 2009 Feb 20;284(8):5352-61. doi: 10.1074/jbc.M805768200. Epub 2008 Dec 1.