Persing J A, Babler W J, Nagorsky M J, Edgerton M T, Jane J A
Plast Reconstr Surg. 1986 Nov;78(5):594-603. doi: 10.1097/00006534-198611000-00006.
Bilateral coronal suture immobilization was performed in 9-day-old rabbits to simulate the brachycephaly deformity characteristic of coronal synostosis. Growth abnormalities were documented by serial radiographic cephalometry. A "corrective" linear craniectomy procedure was performed on the rabbits with an immobilized coronal suture at 60 days of age. The degree of amelioration of the induced abnormalities by the surgery in these animals was compared with a similar group of animals that had the same surgery plus supplemental implantation of a spring expansion device at the coronal suture craniectomy site. The mean marker separation at the coronal suture was significantly greater (5.61 mm +/- 0.52 SE versus 2.53 mm +/- 0.38 SE; p less than 0.05) following spring expander implantation than with linear craniectomy alone. Similarly, induced anterior cranial base shortening and distortion of craniofacial cephalometrics were more significantly improved by the additional use of the spring expansion device.
对9日龄家兔进行双侧冠状缝固定，以模拟冠状缝早闭所特有的短头畸形。通过系列放射学头颅测量记录生长异常情况。在60日龄时，对冠状缝固定的家兔进行“矫正性”线性颅骨切除术。将这些动物手术对诱发异常的改善程度与另一组相似动物进行比较，后者在冠状缝颅骨切除部位进行相同手术并额外植入弹簧扩张装置。与单纯线性颅骨切除术相比，植入弹簧扩张器后冠状缝处标记物的平均间距显著更大（分别为5.61毫米±0.52标准误和2.53毫米±0.38标准误；p<0.05）。同样，额外使用弹簧扩张装置能更显著地改善诱发的前颅底缩短和颅面头颅测量的变形。
