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本文引用的文献

1
Antipsychotic medication and oropharyngeal dysphagia: systematic review.抗精神病药物与口咽吞咽困难:系统评价
Eur J Gastroenterol Hepatol. 2017 Dec;29(12):1332-1339. doi: 10.1097/MEG.0000000000000983.
2
Antipsychotic Use and Risk of Hospitalization or Death Due to Pneumonia in Persons With and Those Without Alzheimer Disease.抗精神病药物的使用与患有和未患有阿尔茨海默病的人因肺炎住院或死亡的风险
Chest. 2016 Dec;150(6):1233-1241. doi: 10.1016/j.chest.2016.06.004. Epub 2016 Jun 11.
3
Biological perspectives: Choking and antipsychotics: is this a significant concern?生物学视角:噎食与抗精神病药物:这是一个重大问题吗?
Perspect Psychiatr Care. 2014 Apr;50(2):79-82. doi: 10.1111/ppc.12062. Epub 2014 Mar 7.
4
Risperidone-induced tardive pharyngeal dystonia presenting with persistent Dysphagia: a case report.利培酮诱发迟发性咽部肌张力障碍伴持续性吞咽困难:一例报告
Prim Care Companion J Clin Psychiatry. 2008;10(2):161-2. doi: 10.4088/pcc.v10n0213b.
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Risperidone and dysphagia.利培酮与吞咽困难。
J Postgrad Med. 2006 Oct-Dec;52(4):327-8.
6
Dysphagia associated with risperidone therapy.与利培酮治疗相关的吞咽困难。
Dysphagia. 2003 Fall;18(4):274-5. doi: 10.1007/s00455-003-0006-x.
7
Sudden dysphagia with uvular enlargement following the initiation of risperidone which responded to benztropine: was this an extrapyramidal side effect?利培酮治疗开始后出现伴有悬雍垂肿大的突发性吞咽困难,对苯海索有反应:这是锥体外系副作用吗?
Gen Hosp Psychiatry. 2001 Jul-Aug;23(4):231-2. doi: 10.1016/s0163-8343(01)00145-1.
8
Reversible dysphagia associated with neuroleptic treatment.
J Am Geriatr Soc. 2001 Sep;49(9):1260-1. doi: 10.1046/j.1532-5415.2001.49249.x.
9
The current status of tardive dystonia.迟发性肌张力障碍的现状
Biol Psychiatry. 1999 Mar 15;45(6):715-30. doi: 10.1016/s0006-3223(98)00242-x.
10
Managing antipsychotic-induced acute and tardive dystonia.管理抗精神病药物引起的急性和迟发性肌张力障碍。
Drug Saf. 1998 Jul;19(1):57-72. doi: 10.2165/00002018-199819010-00005.

与利培酮相关的可逆性吞咽困难伴呛咳发作。

Reversible Dysphagia Associated With Risperidone Presenting With a Choking Episode.

作者信息

Pandit Shradha, Mahat Krishna

机构信息

Internal Medicine, Bandipur Hospital, Bandipur, NPL.

Internal Medicine, Ascension St. John Hospital, Detroit, USA.

出版信息

Cureus. 2023 Jul 26;15(7):e42491. doi: 10.7759/cureus.42491. eCollection 2023 Jul.

DOI:10.7759/cureus.42491
PMID:37637547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10455044/
Abstract

Dysphagia has been associated with antipsychotic drug use. This case report describes the management of dysphagia in a psychiatric patient who presented to the emergency department from a psychiatric facility after choking on a hot dog. The patient was on risperidone 4 mg, initiated a month prior to treat acute psychosis. Foreign body removal from the distal trachea was performed by bronchoscopy, followed by a swallow evaluation by the speech and swallow team. The patient exhibited severe oropharyngeal dysphagia, leading to aspiration pneumonia and subsequent enteral feeding through a nasojejunal tube. Changes in medication from risperidone to aripiprazole, along with a short course of benztropine and dietary modifications, were implemented, with gradual improvement in swallowing function observed during the hospital stay. The patient's complex medical and psychiatric history contributed to a prolonged hospital stay.

摘要

吞咽困难与抗精神病药物的使用有关。本病例报告描述了一名精神病患者吞咽困难的处理情况,该患者在食用热狗时窒息后从精神病院被送往急诊科。患者正在服用4毫克利培酮,该药在一个月前开始使用以治疗急性精神病。通过支气管镜从远端气管取出异物,随后由言语和吞咽治疗团队进行吞咽评估。患者表现出严重的口咽吞咽困难,导致吸入性肺炎,随后通过鼻空肠管进行肠内喂养。实施了从利培酮到阿立哌唑的药物更换,以及短期使用苯海索和饮食调整,住院期间吞咽功能逐渐改善。患者复杂的医疗和精神病史导致住院时间延长。