Fowler Alexander J, Brayne Adam B, Pearse Rupert M, Prowle John R
Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Broomfield Hospital, Mid and South Essex NHS Foundation Trust, Chelmsford, Essex, UK.
BJA Open. 2023 Jun 15;7:100142. doi: 10.1016/j.bjao.2023.100142. eCollection 2023 Sep.
Postoperative complications are associated with reduced long-term survival. We characterise healthcare use changes after sentinel postoperative complications.
We linked primary and secondary care records of patients undergoing elective surgery at four East London hospitals (2012-7) with at least 90 days follow-up. Complication codes (wound infection, urinary tract infection, pneumonia, new stroke, and new myocardial infarction) recorded within 90 days of surgery were identified from primary or secondary care. Outcomes were change in healthcare contact days in the 2 yr before and after surgery, and 2 yr mortality. We report rate ratios (RaR) with 95% confidence intervals and adjusted for baseline healthcare use and confounders using negative binomial regression.
We included 49 913 patients (median age 49 yr [inter-quartile range {IQR}: 34-64]), 27 958 (56.0%) were female. Amongst 3883 (7.8%) patients with complications (median age 58 [IQR: 43-72]), there were 18.4 days per year in contact with healthcare before surgery and 25.3 days after surgery (RaR: 1.38 [1.37-1.39]). Patients without complications (median age 48 [IQR: 33-63]) had 12.3 days per year in contact with healthcare before surgery and 14.0 days after surgery (RaR: 1.14 [1.14-1.15]). The adjusted incidence rate ratio of days in contact with healthcare associated with complications was 1.67 (1.49-1.87). More patients (391; 10.1%) with complications died within 2 yr than those without (1428; 3.1%).
Patients with postoperative complications are older with greater healthcare use before surgery. However, their absolute and relative increases in healthcare use after surgery are greater than patients without complications.
术后并发症与长期生存率降低相关。我们对前哨淋巴结活检术后并发症后的医疗保健使用变化进行了特征描述。
我们将伦敦东部四家医院(2012 - 2017年)接受择期手术且随访至少90天的患者的初级和二级医疗记录进行了关联。从初级或二级医疗记录中识别出手术90天内记录的并发症代码(伤口感染、尿路感染、肺炎、新发中风和新发心肌梗死)。结局指标为手术前后2年的医疗接触天数变化以及2年死亡率。我们报告率比(RaR)及其95%置信区间,并使用负二项回归对基线医疗保健使用情况和混杂因素进行调整。
我们纳入了49913例患者(中位年龄49岁[四分位间距{IQR}:34 - 64岁]),其中27958例(56.0%)为女性。在3883例(7.8%)有并发症的患者中(中位年龄58岁[IQR:43 - 72岁]),术前每年有18.4天与医疗保健接触,术后为25.3天(RaR:1.38[1.37 - 1.39])。无并发症的患者(中位年龄48岁[IQR:33 - 63岁])术前每年有12.3天与医疗保健接触,术后为14.0天(RaR:1.14[1.14 - 1.15])。与并发症相关的医疗接触天数的调整发病率比为1.67(1.49 - 1.87)。有并发症的患者在2年内死亡的人数更多(391例;10.1%),高于无并发症的患者(1428例;3.1%)。
术后有并发症的患者年龄较大,术前医疗保健使用更多。然而,他们术后医疗保健使用的绝对增加量和相对增加量均大于无并发症的患者。