Lammer J, Pilger E, Neumayer K, Schreyer H
Radiology. 1986 Oct;161(1):159-63. doi: 10.1148/radiology.161.1.3763859.
Intraarterial fibrinolytic therapy was performed in 136 patients suffering from arteriosclerotic thrombosis of the iliac and femoropopliteal arteries. The initial success rate was 78%. Despite anticoagulation therapy, early recurrent thrombosis was observed in 10% of the patients. The 2-year cumulative patency rate after recanalization was 81%. These results are competitive with those of reconstructive vascular surgery. Therefore, intraarterial fibrinolysis has become a viable alternative to surgery in treating segmental peripheral occlusions more than 4 cm in length that are less than 6-9 months in duration.
对136例患有髂动脉和股腘动脉粥样硬化血栓形成的患者进行了动脉内溶栓治疗。初始成功率为78%。尽管进行了抗凝治疗,但仍有10%的患者出现早期复发性血栓形成。再通后2年的累积通畅率为81%。这些结果与血管重建手术的结果具有可比性。因此,对于长度超过4 cm、病程小于6至9个月的节段性外周闭塞,动脉内溶栓已成为一种可行的手术替代方法。