René Rachou Institute, Oswaldo Cruz Foundation, Belo Horizonte, Brazil.
Laboratory of Epidemiology of Infectious and Parasitic Diseases, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Am J Trop Med Hyg. 2023 Aug 28;109(4):791-803. doi: 10.4269/ajtmh.23-0017. Print 2023 Oct 4.
We used spatial analysis tools to examine the epidemiological situation and spatial distribution of American tegumentary leishmaniasis in the municipality of Caratinga between 2016 and 2021. In addition, potential sandfly vectors were captured. All information used in this study was retrieved from public health archives and confirmed in the state health services databases. All cases were analyzed using Geographic Information Systems software. In addition, sandfly collections and molecular detection of Leishmania were carried out in areas with the highest number of cases. During the analyzed period, American tegumentary leishmaniasis (ATL) cases increased and remained high in the last years. The hotspots included urban areas of Caratinga city and the districts of Patrocínio of Caratinga and Sapucaia. The species Nyssomyia whitmani, Nyssomyia intermedia, and Migonemyia migonei were the most abundant species and the ITS1-polymerase chain reaction technique detected Leishmania DNA in these species. On the basis of our analyses, the urbanization of ATL in Caratinga has taken place in recent years. Because of the increase in the number of human cases and the presence of vectors, it is recommended that health authorities focus on control measures in hotspots.
我们使用空间分析工具来研究 2016 年至 2021 年期间卡塔林加市的美洲皮肤利什曼病的流行病学情况和空间分布。此外，还捕获了潜在的沙蝇媒介。本研究中使用的所有信息均从公共卫生档案中检索，并在州卫生服务数据库中得到确认。所有病例均使用地理信息系统软件进行分析。此外，在病例数量最多的地区进行了沙蝇采集和利什曼原虫的分子检测。在分析期间，美洲皮肤利什曼病（ATL）的病例增加，并在最近几年保持高位。热点包括卡塔林加市的城区以及卡塔林加的帕特罗西尼奥和萨普卡伊亚区。最丰富的物种是 Nyssomyia whitmani、Nyssomyia intermedia 和 Migonemyia migonei，这些物种中的 ITS1-聚合酶链反应技术检测到了利什曼原虫 DNA。基于我们的分析，近年来卡塔林加的 ATL 已经发生了城市化。由于人类病例数量的增加和媒介的存在，建议卫生当局将重点放在热点地区的控制措施上。
