Biotechnology Department, "Prof. Dr Assen Zlatarov" University, Burgas, Bulgaria.
Genetic Department, "St. Kliment Ohridski" University, Sofia, Bulgaria.
J Am Nutr Assoc. 2024 Feb;43(2):213-220. doi: 10.1080/27697061.2023.2251557. Epub 2023 Aug 28.
The majority (about 70%) of the world's population suffers from lactose intolerance. Lactose intolerance leads to long-term discomfort when consuming milk and dairy products, and hence, to their avoidance. Consequently, the intake of important nutrients is reduced, which potentially has a negative impact on the overall health. Knowing the condition - lactose intolerance - will prevent people from unnecessarily restricting dairy products in their diets. In this study, lactose synthesis and catabolism in the human body are presented, also the types of lactose intolerance, as well as the methods of diagnosing this condition, are discussed. Special attention is paid to the genetic causes of this discomfort and to the tests that can be performed. Solutions for the treatment of lactose intolerance have also been proposed, both up-to-date and easily applicable, as well as future developments.
世界上约有 70%的人口患有乳糖不耐受症。乳糖不耐受症会导致人们在食用牛奶和奶制品时长期感到不适，从而避免食用它们。因此，重要营养物质的摄入量减少，这可能对整体健康产生负面影响。了解乳糖不耐受症这种情况可以防止人们不必要地限制饮食中的乳制品。本研究介绍了人体中乳糖的合成和分解代谢，以及乳糖不耐受的类型，以及诊断这种情况的方法。特别关注这种不适的遗传原因以及可以进行的测试。还提出了一些针对乳糖不耐受症的治疗方法，既有最新的方法，也有易于应用的方法，以及未来的发展方向。
