Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Sci Rep. 2023 Aug 28;13(1):14015. doi: 10.1038/s41598-023-41112-6.
Although there was no significant heterogeneity in the meta-publication, sensitivity analyses revealed significant heterogeneity. Overall, the prevalence was higher in women (N = 6, R = 4.6%, 95% CI 3.1%, 6.0%, and I = 99.8%) than in men (N = 6, R = 3.4%, 95% CI 2.0%, 4.7%, and I = 99.6the %); prevalence of type 2 diabetes (N = 9, R = 12.5%, 95% CI 7.7%, 17.3%, and I = 95.4%) was higher than type 1 diabetes (N = 7, R = 8.3%, 95% CI 6.4%, 10.2%, and I = 93.6%); the prevalence of DGP was slightly lower in DM patients aged over 60 years (N = 6, R = 5.5%, 95% CI 3.3%, 7.7%, and I = 99.9%) compared to patients under 60 years of age (N = 12, R = 15.8%, 95% CI 11 15.8%, 95% CI 11.4%, 20.2%, and I = 88.3%). In conclusion, our findings indicate that the combined estimated prevalence of gastroparesis in diabetic patients is 9.3%. However, the sensitivity of the results is high, the robustness is low, and there are significant bias factors. The subgroup analysis revealed that the prevalence of DM-DGP is associated with factors such as gender, diabetes staging, age, and study method.
尽管元分析中没有显著的异质性,但敏感性分析显示存在显著的异质性。总体而言,女性(N=6,R=4.6%,95%CI 3.1%,6.0%,I=99.8%)的患病率高于男性(N=6,R=3.4%,95%CI 2.0%,4.7%,I=99.6%);2 型糖尿病(N=9,R=12.5%,95%CI 7.7%,17.3%,I=95.4%)的患病率高于 1 型糖尿病(N=7,R=8.3%,95%CI 6.4%,10.2%,I=93.6%);60 岁以上的糖尿病患者(N=6,R=5.5%,95%CI 3.3%,7.7%,I=99.9%)的 DGP 患病率略低于 60 岁以下的糖尿病患者(N=12,R=15.8%,95%CI 11.4%,20.2%,I=88.3%)。总之,我们的研究结果表明,糖尿病患者胃轻瘫的合并估计患病率为 9.3%。然而,结果的灵敏度较高,稳健性较低,存在显著的偏倚因素。亚组分析显示,DM-DGP 的患病率与性别、糖尿病分期、年龄和研究方法等因素有关。