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放射学在幼年特发性关节炎的诊断、监测和预后中的作用。

The role of radiography in diagnosing, monitoring and prognosing juvenile idiopathic arthritis.

机构信息

Department of Radiology, University Children's Hospital Ljubljana, University Medical Center Ljubljana, Bohoričeva 20, 1000, Ljubljana, Slovenia.

Department of Radiology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Pediatr Radiol. 2024 Apr;54(4):481-489. doi: 10.1007/s00247-023-05742-2. Epub 2023 Aug 29.

DOI:10.1007/s00247-023-05742-2
PMID:37640799
Abstract

The current role of conventional radiography in the diagnosis, monitoring and prognosis of juvenile idiopathic arthritis (JIA) is reviewed, as its role has changed with the increasing use of ultrasound and magnetic resonance imaging, as well as with the introduction of biological drugs. Conventional radiography does not play an important role in the diagnosis of JIA, as this is based on history, clinical examination and laboratory findings. The main role of conventional radiography is in the detection and monitoring of growth disorders and chronic structural and morphological changes of the affected joints and bones, in addition to helping with the differential diagnosis of conditions that mimic JIA. Radiographic changes of the joints depend on the age of the child, the type and duration of arthritis and the specific joints affected. There are no standard protocols for arthritis monitoring and most indications for imaging are based on individual case-by-case decisions. The development of degenerative joint changes is considered a poor predictive factor, but there are no clear studies that more precisely define the predictive value of radiographic changes. Conventional radiography remains an important imaging modality in narrowing the differential diagnosis and in evaluating growth disorders and the developing destructive joint changes.

摘要

本文回顾了传统放射学在幼年特发性关节炎(JIA)的诊断、监测和预后中的作用,因为随着超声和磁共振成像的广泛应用以及生物药物的引入,其作用发生了变化。传统放射学在 JIA 的诊断中并没有重要作用,因为它是基于病史、临床检查和实验室发现的。传统放射学的主要作用是检测和监测生长障碍以及受累关节和骨骼的慢性结构和形态变化,此外还可帮助鉴别模仿 JIA 的疾病。关节的放射学变化取决于儿童的年龄、关节炎的类型和持续时间以及特定受累的关节。关节炎监测没有标准方案,大多数影像学检查的适应证都是基于个别病例的决策。退行性关节变化的发展被认为是一个预后不良的因素,但没有明确的研究更精确地定义放射学变化的预测价值。传统放射学仍然是一种重要的影像学手段,可以缩小鉴别诊断的范围,并评估生长障碍和正在发展的破坏性关节变化。

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本文引用的文献

1
Foot and Ankle Conventional Radiography in Juvenile Idiopathic Arthritis: Does It Still Matter?青少年特发性关节炎的足踝部传统放射摄影:它仍然重要吗?
J Belg Soc Radiol. 2022 Sep 23;106(1):87. doi: 10.5334/jbsr.2729. eCollection 2022.
2
Radiographs and MRI of the Cervical Spine in Juvenile Idiopathic Arthritis: A Cross-Sectional Retrospective Study.青少年特发性关节炎颈椎的X线片和磁共振成像:一项横断面回顾性研究
J Clin Med. 2021 Dec 11;10(24):5798. doi: 10.3390/jcm10245798.
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Hip Involvement in Juvenile Idiopathic Arthritis: A Roadmap From Arthritis to Total Hip Arthroplasty or How Can We Prevent Hip Damage?
儿童风湿性肌肉骨骼疾病的影像学评估
Skeletal Radiol. 2025 Mar 29. doi: 10.1007/s00256-025-04910-9.
青少年特发性关节炎累及髋关节:从关节炎到全髋关节置换术的路线图,或我们如何预防髋关节损伤?
Front Pediatr. 2021 Nov 5;9:747779. doi: 10.3389/fped.2021.747779. eCollection 2021.
4
Biomarkers of Response to Biologic Therapy in Juvenile Idiopathic Arthritis.幼年特发性关节炎生物治疗反应的生物标志物
Front Pharmacol. 2021 Feb 2;11:635823. doi: 10.3389/fphar.2020.635823. eCollection 2020.
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Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis: ESSR-ESPR points to consider.疑似或已知幼年特发性关节炎患儿的影像学评估:ESSR-ESPR 需考虑要点。
Eur Radiol. 2020 Oct;30(10):5237-5249. doi: 10.1007/s00330-020-06807-8. Epub 2020 May 12.
6
The role of imaging in juvenile idiopathic arthritis.影像学在幼年特发性关节炎中的作用。
Expert Rev Clin Immunol. 2018 Aug;14(8):681-694. doi: 10.1080/1744666X.2018.1496019. Epub 2018 Jul 20.
7
A novel radiographic scoring system for growth abnormalities and structural change in children with juvenile idiopathic arthritis of the hip.一种用于评估髋关节幼年特发性关节炎患儿生长异常和结构改变的新型影像学评分系统。
Pediatr Radiol. 2018 Aug;48(8):1086-1095. doi: 10.1007/s00247-018-4136-6. Epub 2018 May 1.
8
Conventional radiography in juvenile idiopathic arthritis: Joint recommendations from the French societies for rheumatology, radiology and paediatric rheumatology.幼年特发性关节炎的常规放射学检查:法国风湿病学会、放射学会和儿科风湿病学会的关节推荐意见。
Eur Radiol. 2018 Sep;28(9):3963-3976. doi: 10.1007/s00330-018-5304-7. Epub 2018 Mar 26.
9
Imaging of juvenile idiopathic arthritis. Part I: Clinical classifications and radiographs.幼年特发性关节炎的影像学。第一部分:临床分类与X线片
J Ultrason. 2016 Sep;16(66):225-36. doi: 10.15557/JoU.2016.0023. Epub 2016 Sep 7.
10
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Radiographics. 2013 Sep-Oct;33(5):1253-73. doi: 10.1148/rg.335125178.